Prenatal diagnosis has been performed on umbilical cord blood of an 18 weeks fetus of heterozygous triosephosphate isomerase (TPI) deficient parents. After excluding maternal blood contamination, TPI activity was measured and found to be 60 per cent of the normal mean whereas the value of glucose-6-phosphate dehydrogenase activity was in the normal range of fetal blood. In addition, the analysis of the characteristics of fetal TPI, i.e. Km measurements for glyceraldehyde-3-phosphate, heat stability tests and electrophoretic studies, did not show any evidence of a special form of TPI in fetal blood. These results were consistent with the heterozygous state and were confirmed at birth.

Anemia, Hemolytic, Congenital↗

PubMedDate not supplied

Behavioral and monoaminergic changes after lindane exposure in developing rats.

The effects of lindane on behavior and central monoaminergic systems were studied in rat pups at 15 days of postnatal age. Pups were previously given nonconvulsant lindane PO doses, either a single 20 mg/kg or 7-day repeated 10 mg/kg doses. Both treatment schedules improved the passive avoidance acquisition but only the acute administration prolonged the step-through latency. Acute lindane decreased the motor activity, whereas the repeated dosing increased it. Increases of the ratio 5-HIAA/serotonin in several brain regions and of the ratio DOPAC/dopamine in the mesencephalon after a single dose of lindane suggest an enhanced monoaminergic turnover. In contrast, repeated lindane doses decreased monoamine/metabolite ratios excluding the striatum, where an increase of DOPAC/dopamine ratio correlates with the higher motor activity of these animals. It is postulated that both the imbalance of the central monoaminergic systems and the lindane-induced GABAergic blockade may be the basis of the behavioral alterations.

Animals↗

PubMedDate not supplied

[Triatoma platensis Neiva, 1913 (Hemiptera, Triatominae) found in the Brazilian state of "Rio Grande do Sul"].

Triatoma platensis, an ornitophilic species, found in Argentina, Bolivia, Paraguay and Uruguay is reported for the first time in Brazil. It was found in the county of Uruguaiana (Rio Grande do Sul) in nests of Anumbius annumbi (Vieillot, 1817) (Passeriformes, Furnariidae) where it cohabited with cricetids belonging to the species Orizomys flavescens. None of the seven individuals collected were infected by Trypanosoma cruzi.

Animals↗

PubMedDate not supplied

[Triatoma delpontei Romaña & Abalos, 1947 (Hemiptera, Tratominae) in the Brazilian State of Rio Grande do Sul].

Triatoma delpontei (Romaña & Abalos, 1947) (Hemiptera, Triatominae) is an ornithophilic sylvatic with a particular association to the psittacid Myiopsitta monachus (Boaddert, 1783). It is found in the continental biogeographical province of the Chaco, where it inhabits the nests or M. monachus, in subtropical xerophytic forests. The authors report the first finding of T. delpontei in Brasil, in the "campanha" region of the State or Rio Grande do Sul (Barra do Quarai, Uruguaiana), on the right bank of the River Cuareim, not far from de Uruguayan border.

Animals↗

PubMedDate not supplied

[Feeding pattern of Triatoma rubrovaria (Blanchard, 1843) (Hemiptera, Triatominae) in peridomiciliary habitats, of a rural area of Uruguay].

It has been studied the feeding patterns of Triatoma rubrovaria (wild triatominae bug, and intradomiciliary secondary vector of T. cruzi) in a rural area of "La Bolsa" (Department of Artigas). Agar double diffusion test were used for analyze the blood meal, from 120 insects, which were confronted to 13 antisera. It has 251 identify blood meals, and the most frequently was mammalian host (73%), but it has a variable source of feeding (mammals, birds, reptiles and cockroach), including humans rate 8% of the total. The identify of haemolimphe as feed, place this triatominae bug as an intermediary vector between predator and haematophagous. The most usual mammals are dasypodides and bovines. The frequence of human blood meal near the dwellings, shows its potentiality as vectors. Therefore, the peridomicile is an area of interaction between, domestic, wild and sinantropic host. The trypanosomic infection's rate at peridomiciles was lesser those at wild areas.

Animals↗

PubMedDate not supplied

Ecology of Triatoma rubrovaria (Hemiptera, Triatominae) in wild and peridomestic environments of Uruguay.

This paper describes population structure, spatial distribution and habitat selection of wild and peridomestic populations of Triatoma rubrovaria (Blanchard, 1843). Field studies were carried out at Las Piedras and La Bolsa in the Northern Department of Artigas, Uruguay. A semicircular sampling area, divided in seven or eight triangular sectors was sequentially examined from October 1990 to November 1991. At Las Piedras (typical wild habitat) 1063 T. rubrovaria bugs were collected from 84% of the rocky outcroops ("pedregales"). Abundance varied by season peaking in October-November (spring). Throughout the year, most of the population was made up of third, fourth and fifth instar nymphs; adults were found from October to March. In the peridomestic environment of La Bolsa, however T. rubrovaria was less common and showed a more irregular instar distribution. Colonized ecotopes, were those close to houses. In both sites T. rubrovaria was mainly associated with the geckonid Homonota uruguayensis and the cockroach Blaptica dubia.

Animals↗

PubMedDate not supplied

[Seroprevalence of T. cruzi infection in 6- and 12- year-old school children from three Uruguayan endemic departments].

The last national survey on seroprevalence of T. cruzi human infection in Uruguay, showed a 3.4% in adults from endemic areas. Since 1983, antivectorial actions of the control program have been carried out continually. In consequence, household infestation by Triatoma infestan, the main vector of T. cruzi in Uruguay, decreased in all endemic areas and was completely eliminated in some of them. The objectives of the present work are to evaluate the new seroepidemiological situation. A representative sampling of rural and urban population was undertaken, to include six and twelve year-old school children from three departments: Artigas, Rivera and Tacuarembo. The whole sample included 4,722 school children, evaluated by the indirect immunofluorescence (IFI) test for Chagaś disease. The seroprevalence of T. cruzi infection in the six year-old group was 0.3% in Artigas, 0.6% in Rivera and 1.0% in Tacuarembo. The seropositive children with seropositive mothers support the possible congenital transmission.

Animals↗

PubMedDate not supplied

[Local anesthesia for heart disease patients in dentistry].

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Adolescent↗

PubMedDate not supplied

[Seminar on composite resins in posterior teeth].

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Bicuspid↗

PubMedDate not supplied

[Abdominal aortic aneurysm associated with non-neoplastic abdominal disease. Therapeutic approach].

BACKGROUND: Personal experience concerning the treatment of 8 patients with infrarenal aortic aneurysms associated with extravascular non-neoplastic abdominal diseases is presented. METHODS AND RESULTS: In all 7 cases which underwent combined surgical procedures (aneury-smectomy + cholecystectomy in 4 patients and aneurysmectomy + groin hernia repair in 3 patients) early and late postoperative complications were not recorded. CONCLUSIONS: The main therapeutic guidelines concerning the pathologic association of infrarenal aortic aneurysms associated with extravascular non-neoplastic abdominal diseases are discussed on the basis of a literature review and of personal experience.

Adult↗