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Biomedical subjects

R Renslo

Publications and source records attributed to R Renslo.

11 recordsLinked to original sources
PubMed2001

Prenatal cocaine exposure and cranial sonographic findings in preterm infants.

PURPOSE: Prenatal cocaine exposure has been linked with subependymal hemorrhage and the formation of cysts that are detectable on cranial sonography in neonates born at term. We sought to determine if prenatal cocaine exposure increases the incidence of subependymal cysts in preterm infants. METHODS: We retrospectively reviewed the medical records and cranial sonograms obtained during a 1-year period on 122 premature (< 36 weeks of gestation) infants. Infants were categorized into 1 of 2 groups: those exposed to cocaine and those not exposed to cocaine. Infants were assigned to the cocaine-exposed group if there was a maternal history of cocaine abuse during pregnancy or if maternal or neonatal urine toxicology results were positive at the time of delivery. RESULTS: Five of the 122 infants were excluded from the study because of insufficient medical and drug histories. The incidence of subependymal cysts in the 117 remaining infants was 14% (16 of 117). The incidence of subependymal cysts in infants exposed to cocaine prenatally was 44% (8 of 18) compared with 8% (8 of 99) in the unexposed group (p < 0.01). CONCLUSIONS: We found an increased incidence of subependymal cyst formation in preterm infants who were exposed to cocaine prenatally. This result is consistent with results of similar studies in term infants.

Brain Diseases↗
PubMed2000

Correlation between admission laboratory values, early abdominal computed tomography, and severe complications of gallstone pancreatitis.

BACKGROUND: Our previous study demonstrated that Balthazar grade D or E pancreatitis on early abdominal computed tomography (CT) scan correlated with severe complications of gallstone pancreatitis (GP). OBJECTIVE: To compare the efficacy of individual admission laboratory criteria, multiple criteria scoring systems and CT scan for predicting severe complications of GP. METHODS: Consecutively admitted patients with GP underwent selective early CT scanning (<72 hours). All patients were prospectively monitored for severe complications. RESULTS: Of the 66 patients studied, 21 (32%) did not undergo for early CT scanning and underwent cholecystectomy with no complications. Forty-five patients (68%) had an early abdominal CT scan. Of the 12 patients with grade E pancreatitis, 6 (50%) developed severe complications versus only 2 of 33 (6%) with grade A to D pancreatitis (P = 0.002). A significant correlation was found between admission white blood cell count > or =14.5 x 10(9)/L and grade E pancreatitis on early CT scan (P = 0.002). However, admission glucose > or =150 mg/dL was the best predictor of complications (sensitivity 100%, negative predictive value 100%). CONCLUSION: Although Balthazar grade E on early CT scan correlates with severe complications of GP, admission glucose > or =150 mg/dL has a better sensitivity and negative predictive value, is quicker to use, and is more cost-effective as a prognostic indicator.

Acute Disease↗
PubMed1998

Clinically silent primary adrenal lymphoma: a case report and review of the literature.

Primary adrenal lymphoma (PAL) is extremely uncommon. We describe a case of clinically silent non-Hodgkin's B-cell lymphoma of diffuse large cell type with exclusive left adrenal localization. The tumor was discovered by computed tomography (CT) as a 2.5-cm dense mass and diagnosed at autopsy. Literature concerning this unusual neoplasm is reviewed. During the early stage, particularly when the lesion is small, PAL is likely to be missed. This unusual entity should be included in the differential diagnosis of adrenal masses so that early diagnosis may be made and intervention might dramatically affect the clinical outcome.

Adrenal Gland Neoplasms↗
PubMed1998

Learning curve in the use of the radial artery as vascular access in the performance of percutaneous transluminal coronary angioplasty.

Radial artery access for coronary artery angioplasty is a cost-effective alternative to other vascular entry sites. The initial series of patients using the radial artery site for an operator without experience in using arm access for coronary artery angioplasty was evaluated. Clinical success was achieved via the radial artery in 87% of 32 lesions and 84% of 27 patients. The major feature limiting success via the arm was radial/brachial artery spasm, which occurred in 30% of cases (clinical success: 50% with spasm vs. 95% without spasm, P < 0.05). Spasm was more common in patients with peripheral vascular disease and in hypertensive patients not treated with calcium channel blockers prior to angioplasty. Coronary angioplasty via the radial artery may be successfully performed even by the interventionalist inexperienced in arm access. Vascular spasm is an important feature that limits the ability successfully to complete coronary angioplasty via the radial artery.

Angioplasty, Balloon, Coronary↗
PubMed1997

CT guided needle localization for video-thoracoscopic resection of pulmonary nodules.

Because of its decreased invasiveness Video-Assisted Thoracoscopic Surgery (VATS) has advantages over the traditional open thoracotomy. However, resection of small and subpleural pulmonary nodules via the thoracoscope is often technically difficult or impossible. To facilitate the resection of these difficult-to-palpate lesions, a protocol was established to localize the nodules percutaneously with a fine needle under CT guidance. This method was used in four patients to localize five lung lesions identified radiographically in various lung segments. Of the four patients in the study, three presented with malignancy of the lower extremities (alveolar sarcoma, squamous cell carcinoma, and spindle cell carcinoma). In two of these patients (having alveolar sarcoma and spindle cell carcinoma primaries), the resected pulmonary lesions proved to be metastatic disease. The lesions of the other two patients were nonmalignant (actinomycosis and fibrotic granuloma). The patients with actinomycosis had two distinct lesions which were identified preoperatively with two localizations. All five lesions were able to be localized and resected with clear margins. The patients tolerated the procedures well without complication. VATS with preoperative CT guided needle localization of a subpleural nodule can be a useful diagnostic tool. Its use in therapeutic metastasectomy, nonetheless, remains controversial.

Actinomycosis↗
PubMed1997

Early computed tomography is rarely necessary in gallstone pancreatitis.

The role of early CT scanning in acute gallstone pancreatitis remains ill defined. The purpose of our study was to: 1) determine whether our previously identified admission prognostic factors for gallstone pancreatitis [white blood cell (WBC) count > or = 14.5 x 10(9)/L, blood urea nitrogen (BUN) > or = 12 mmol/L, Acute and Chronic Health Evaluation II score > or = 5, glucose > or = 150 mg/dL, and heart rate > or = 100 beats/min)] correlate with the severity of pancreatic inflammation on CT scan, and 2) to determine the utility of early CT scanning in the management of gallstone pancreatitis. Admission clinical and laboratory variables were collected prospectively. Early CT scan findings were graded using the Balthazar scoring system and subgrouped into mild-moderate (Balthazar grades A-C) or severe (grades D and E) by a radiologist blinded to the patients' clinical status. Ninety-seven patients underwent surgery during their initial hospitalization without preoperative CT scanning. Four had operative complications (4%). Forty-two patients underwent early CT scan (grade A, 19%; B, 5%; C, 21%; D, 10%; and E, 45%), but only four (all grade E) had surgery delayed because of necrotizing pancreatitis, abscess, or pseudocyst. All four had persistent abdominal pain. There was one (2.5%) operative complication in the CT group and no deaths. Admission WBC count > or = 14.5 x 10(9)/L and BUN > or = 12 mmol/L correlated with severe pancreatitis (grades D and E) on CT (P < .05). We conclude that in patients with gallstone pancreatitis, 1) admission WBC count > or = 14.5 x 10(9)/L and BUN > or = 12 mmol/L correlate with the severity of pancreatic inflammation on CT scan, and 2) CT scan findings rarely influence management decisions and CT is therefore unnecessary, except in the minority of patients with objective indications of severe or unresolving pancreatitis.

APACHE↗
PubMed1996

Effect of exercise training on energy expenditure, muscle volume, and maximal oxygen uptake in female adolescents.

OBJECTIVES: American female adolescents are at high risk of a physically inactive lifestyle that likely leads to health problems later in life. We hypothesized that a brief program of endurance exercise training in female adolescents would result in increased energy expenditure and quantifiable structural and functional adaptations. STUDY DESIGN: Forty-four high school girls (aged 15 to 17 years, none were elite athletes) enrolled in a 5-day per week anatomy class for 5 weeks and were randomly assigned to control (n = 22) and training groups. All subjects participated in a 2-hour daily teaching program. During the remaining time (2 hours), the training group members underwent endurance-type training and control group subjects participated in a computer workshop. The intervention was assessed by (1) comparison of total energy expenditure between groups with the doubly labeled water technique, (2) determination of changes in thigh muscle volume by magnetic resonance imaging, and (3) determination of changes in maximal oxygen uptake by use of respiratory gas exchange responses. RESULTS: Total energy expenditure was significantly greater (15.3%) in the training group compared with the control subjects (p < 0.003). Five weeks of training led to a 4.3% +/- 1% increase in thigh muscle volume (p < 0.0002) and a 12.1% +/- 3.7% increase in maximal oxygen uptake (p < 0.004); there were no changes in the control group. The training effect was most pronounced in the least fit subjects. CONCLUSIONS: Exercise training programs for female adolescents can be successfully integrated into a high school summer curriculum. Quantifiable, substantial structural and functional responses occur with relatively short periods of training. Approximately 60% of the training response was related to factors independent of muscle size per se. These data may serve to better design physical activity programs for female adolescents.

Adolescent↗
PubMed1995

Endovaginal ultrasonographically guided transvaginal drainage for treatment of pelvic abscesses.

OBJECTIVE: This study assessed the ability of endovaginal ultrasonographically directed transvaginal drainage of pelvic abscesses to treat patients who failed intravenous antibiotic therapies and whose abscesses were not amenable to percutaneous or colpotomy drainage. STUDY DESIGN: Thirty-one women who would otherwise have required surgery to treat their pelvic abscesses underwent the procedure. Immediate clinical response and longer-term follow-up results were collected retrospectively. RESULTS: Thirty-four procedures were performed on 31 women. Purulent material (10 to 350 ml) was aspirated in every case. Twenty-six of the 31 women (84%) were successfully treated by drainage. In the 6- to 21-month follow-up period, 10 women remained without problems, eight had sequelae related to pelvic infection, and eight were lost to follow-up. CONCLUSION: Endovaginal ultrasonographically guided transvaginal drainage is a safe, effective procedure for treatment of pelvic abscesses and should be considered the route of choice for draining collections not amenable to percutaneous or colpotomy drainage.

Abscess↗
PubMed1993

MR mammographic localization. Work in progress.

The authors present phantom test results for a stereotaxic device that may permit simple, rapid, and accurate needle biopsy and localization of breast lesions detected at contrast material-enhanced magnetic resonance (MR) mammography. The mechanical accuracy of this prototype MR breast localizer is approximately plus or minus 3.5 mm at 5 cm.

Biopsy, Needle↗