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Biomedical subjects

R Renaud

Publications and source records attributed to R Renaud.

At least 91 records · Page 5Linked to original sources

[Involuntary leakage of urine in women].

Involuntary leakage of urine in women is often the result of ill-understood pathological conditions which, it seems to us, can most often be related to neurological troubles or to post-operative urethral scarring with or without weak sphincter action associated with urethral instability. They are responsible for a large fraction of the poor results that have been obtained after treatment of bladder instability or of urinary incontinence due to the transmission defect. They should be looked for carefully in every pre-treatment work-out of a patient. The treatment consists mainly in using oestrogen and in re-educating the sphincter muscles with the help of a biofeed-back technique, as well as finally giving-anticholinergic drugs. When they are associated with stress incontinence of urine due to faulty transmission they do not represent an absolute contra-indication to surgery, so long as it is understood that the outcome of the surgery will always, in these cases, be less favourable.

Biofeedback, Psychology↗

[Interest of urodynamic exploration in the women with prolapsus].

In a retrospective study of 54 cases of prolapse in the menopausal woman the authors noted problems of urinary continence, in particular stress incontinence and incontinence due to bladder instability, in 40 p. cent of these women. Unfortunately, the clinical diagnosis is often misleading, and is in 65 p. cent of the cases later rectified by urodynamic investigation. Serious therapeutic errors, such as operating a bladder instability mistaken for stress incontinence, or neglecting a potential stress incontinence that could have been easily corrected at the same time as the prolapse operation, can thereby be avoide. In conclusion, the authors stress that an urodynamic exploration, including cystometry and sphincterometry, is absolutely necessary in the regular work-up of the menopausal women with prolapse.

Aged↗

Prenatal diagnosis and postnatal follow-up of an abnormal child with two de novo apparently balanced translocations.

By prenatal diagnosis two apparently unrelated reciprocal translocations involving chromosomes 6/15 and 13/14 were revealed in a fetus in whom echography demonstrated an abdominal tumor. Pregnancy continued. At birth the child had dysmorphia and hydronephrosis, for which surgery was performed. The psychomotor development was delayed. These abnormalities may be the result of the loss of a small amount of chromosomal material accompanying these translocations.

Abdominal Neoplasms↗

[The avoidable neonatal injuries during delivery (author's transl)].

The authors describe their approach which was designed to meet three imperatives, namely: --to prevent severe foetal distress, --to detect severe foetal distress by systematic use of the cardiotocography, --to avoid unnecessary interventions by supervising the metabolic state of the mother and the foetus which makes it possible to distinguish foetal acidosis by hypoxia necessitating rapid intervention from foetal acidosis of maternal origin for which extraction is not generally necessary. Their action has made it possible to reduce the number of caesarian during labour which achieving extremely low perinatal mortality and morbidity rates.

Birth Injuries↗

[Hemoglobinopathies and pregnancy].

The authors, who practised for years in Africa, present the present view on the effects haemoglobinopathies have on pregnancy and on modern therapeutic methods. They point out that among these haemoglobinopathies by far the most serious is haemoglobin SS or heterozygote S associated with haemoglobin C or with betathalassaemia. On the other hand, pregnancies in patients with the sickle-cell trait (HbSA) are often very well tolerated.

Anemia↗

A double-blind investigation into the effects of ritodrine on uterine blood flow during the third trimester of pregnancy.

The object of this double-blind crossover study was to investigate the effect of a beta-mimetic agent-ritodrine-administered intravenously at increasing infusion rates on uterine blood flow and the maternal cardiovascular system during the third trimester of normal pregnancies and pregnancies complicated by intrauterine growth retardation and/or hypertension. Uterine blood flow, maternal arterial blood pressure, maternal and fetal heart rate, and uterine activity were simultaneously recorded throughout the study. In normal pregnancies the changes in different parameters during ritodrine and placebo administration were slight. In the "pathologic" pregnancies there was a highly significant increase in maternal heart rate, differential blood pressure, and uterine blood flow during ritodrine administration. The differences in response to ritodrine and placebo were statistically significant in this later group. This study demonstrates increased sensitivity of the maternal cardiovascular system to this beta-mimetic agent in certain categories of high-risk pregnancies and possibily an increase in uteroplacental blood flow.

Blood Pressure↗