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Biomedical subjects

R Reid

Publications and source records attributed to R Reid.

258 records · Page 15Linked to original sources
PubMedDate not supplied

The biology and significance of human papillomavirus infections in the genital tract.

A variety of human papillomavirus (HPV) types infect the anogenital mucosa, giving rise to lesions that differ in clinical appearance, histology, and risk of malignant progression. Certain high-risk types (HPVs 16, 18, 31, 33, 35 and 39) have a strong association with high-grade epithelial neoplasia and invasive carcinomas of the anogenital tract. Cancer appears to have a multifactorial etiology, and HPV infection alone is probably insufficient for malignant transformation. The consistent association between HPV infection and anogenital cancers emphasizes, however, that the sexually transmitted papillomaviruses may have a necessary role in carcinogenesis. Hence, there is a prospect that vaccination programs may one day allow public health control of HPV infection, thereby eliminating an important risk factor.

Female↗
PubMedDate not supplied

Amyloid disease: association with failure of arterial reconstruction.

Amyloidosis may accompany many chronic diseases and in particular occurs as a complication of myelomatosis in 10% of cases. This paper reports the effects of amyloid in major arteries of the leg, and describes attempts to treat this occlusive disease using vascular grafts. Such disease may be rapidly progressive and its presence may indicate a poor outlook after vascular surgery. Arterial biopsy at the time of operation in patients with diseases associated with amyloidosis may be useful in assessing prognosis.

Amputation, Surgical↗