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Biomedical subjects

R Razzolini

Publications and source records attributed to R Razzolini.

At least 109 records · Page 6Linked to original sources
PubMed1976

[Study of left ventricular function. Part II: systolic perimetric variations (author's transl)].

New parameters for the study of ventricular dynamic, which analyze the perimetric dimensional variations of the ventricular margin on the cineventriculographic projective plain, were introduced. Three usable methods for these determinations are described: 1) the systolic dimensional variation of the total perimeter; 2) the contribution to the total perimetric length and the systolic shortening of the anterior and posterior wall; 3) the contribution of the telediastolic and the telesystolic length to the anterior or posterior wall and the systolic shortening (in mm/m2 of the corporeal surface and in the percentage of the respective telediastolic length) of each marginal region.

Angiocardiography↗
PubMed1976

[Primitive cardiomyopathies: dynamic geometry of left ventricular contraction].

51 patients with primitive cardiomyopathy were studied and classified (5 groups) on the basis of hemodynamic parametres and the modalities of left ventricular contraction: the first group was made up of patients with "frontal sector" hyperkinesia, normal ejection fraction and without any dynamic obstruction of the ventricular flow; the second, of patients with hyperkinesia "frontal and rear sector" raised ejection fraction and with dynamic obstruction; the third group was composed of patients with "frontal sector" hyperkinesia, reduced motility of the mitralic valvular level with appearance of insufficiency (maintained in the subsequent groups) and depression of the ejection fraction; dynamic obstruction was present. Groups IV and V included patients with progressive extension of hypokinesia to all marginal regions, up to the contraction pattern characterized by "serious and diffused hypokinesia". To conclude, a correlation of the contraction patterns is made, characterizing the various groups with a pathophysiological interpretation.

Adult↗
PubMed1976

[Study of normal left ventricular volume (author's transl)].

A study of left ventricular volume was carried out on ten normal subjects. The average values and the standard deviations of the end-diastolic (EDV) and end-systolic volumes (ESV), the systolic throw and the ejection (EF) are reported. They were obtained by using the single-plane cineventriculography method in the OAdx projection of 30 degrees.

Angiocardiography↗
PubMed1976

[Quantitative evaluation of the systolic displacement of the left ventricle profile. A cineventriculographic study (author's transl)].

A new method for evaluating the systolic displacement of the left ventricle profile is proposed. It rests on the definition of an intracardiac axis and the identification of equivalent points on cardiac end-systolic and end-diastolic silhouettes separately. Displacement in then evaluated by means of vector methods. The results in ten normal subjects are reported. Systolic displacement is visualized by means of maps, uhich reflect the geometric properties of left ventricle normal contraction.

Angiocardiography↗
PubMed1976

Aorto-pulmonary relationship, arterio-ventricular alignment, and ventricular septal defects in complete transposition of the great arteries.

A study of the conal anatomy of 36 specimens of complete transposition of the great arteries (TGA) is reported. The aim of the investigation was to verify if the two main anatomic features of the malformation, i.e. abnormal aorto-pulmonary and arterioventricular relationships, were strictly related to the maldevelopment of the conal structures. The findings indicate that in the cases with mitro-pulmonary fibrous continuity, there is a wide variation in subaortic conal development. and no correlation exists between the anterior position of the aorta and the length of the subaortic parietal conus. Therefore, differential conal absorption does not seem to play a role in the presumptive lack of rotation in TGA. TGA presenting with bilateral conus and biventricular pulmonary trunk origin are relatively frequent in this survey, but no correlation was observed between overriding of the pulmonary artery and development of the subpulmonary parietal conus. Consequently, in TGA the morphogenetic process of transfer of the pulmonary artery above the left ventricle does not seem to depend only on the absorption of the subpulomonary parietal conus. Ventricular septal defects (VSDs) in TGA are related frequently to conal pathology, either to some failure in conal septal growth or to malalignment of the normally developed conal and sinusal components of the ventricular septum.

Aorta, Thoracic↗
PubMed1976

[Complete transposition of the great arteries: hypertensiol pulmonary vascular disease in the first six months of life (author's transl)].

Lung specimens of 27 patients under six months of age with complete transposition of the great arteries (TGA), obtained at autopsy, were studied histologically. No evidence of hypertensive pulmonary vascular disease was found in patients under four months of age (23 patients), while obstructive intimal proliferations were seen in 2 patients, aged four and five months, with TGA and VSD. Since pulmonary vascular lesions in transposition with VSD appear early in infancy, timely palliative procedures, such as banding of the pulmonary artery, are strongly indicated when the radical corrective operation is to be postponed.

Humans↗
PubMed1976

[Study of the descending phase of the aortic pressure curve. Possible applications to the monitoring of peripheral resistance and arterial compliance (author's transl)].

In 21 patients aortic pressure was recorded just above the diaphragm. The curve after the dicrotic notch is an exponential function of the time, and it is possible to characterize it by a unique time-constant. This constnat is shown to depend on aortic compliance and peripheral resistance: as aortic compliance does not vary abruptly in physiological conditions, this allows monitoring of peripheral resistance by monitoring time constant. Mathematical bases of time constant and of the peripheral resistance are briefly discussed.

Arteries↗
PubMedDate not supplied

Global and regional left ventricular function in heart transplant patients: an angiographic follow-up study.

We studied the global and regional left ventricular function, its determinants and its modification with time, in orthotopic heart transplant recipients. We reviewed the left ventricular cineangiography performed 1 (50 patients), 2 (33 patients), 3 (18 patients), and 4 (seven patients) years after operation. Regional wall motion was quantitatively evaluated by the area method. All patients had angiographically normal coronary arteries and no evidence of acute rejection at the time of the study. One year after heart transplantation, cardiac index and left ventricular ejection fraction were mildly but significantly lower than normal. Cardiac index was more than 2.5 L/min/m2 in all but one patient, and ejection fraction was more than 50% in all patients. Only previous acute cardiac rejection necessitating therapy and arterial hypertension showed some influence on the left ventricular function. Two years after operation, the left ventricular end-diastolic volume was increased, and left ventricular mass-volume ratio decreased compared with year 1. Three years after operation, an increase of left ventricular end-diastolic pressure and of left ventricular ejection fraction was also evident. Four years after operation, the heart rate was higher, compared with previous years. Even if the changes in the parameters of left ventricular function were significant, they were small in terms of absolute value. Regional hypokinesia was detected 1 year after heart transplantation in eight patients, involving one segment in six patients and two segments in two patients.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗