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Biomedical subjects

R Raz

Publications and source records attributed to R Raz.

168 records · Page 10Linked to original sources

Malaria and Borrelia co-infection.

Severe anemia requiring blood transfusion may complicate falciparum malaria, but is rare in nonfalciparum malaria. We present a case of a young man with high fever, severe hemolytic anemia, and a blood film containing massive co-infection with Plasmodium vivax and with Borrelia. The possible importance of the co-infection on the magnitude of hemolysis will be discussed.

Adult↗

Asymptomatic bacteriuria in institutionalized elders in Israel.

OBJECTIVES: To document the prevalence of asymptomatic bacteriuria in patients in one large long-term care facility, and describe clinical outcomes in initially bacteriuric and nonbacteriuric residents during prospective observation encompassing one year. METHODS: Patients enrolled in the study were residents of the Haim-Shoham Geriatric Center, a long-term care institute with 800 inhabitants. Twenty patients were related randomly for study enrollment on each of the ten wards. A urine culture was obtained from the enrolled patients. A second culture was obtained within one week if the initial culture grew >or= 10(5) colony-forming units per milliliter (cfu/ml) of at least one uropathogen. Demographic data and comorbidities, as well as most recent laboratory results, were recorded for all patients enrolled. Subjects were followed prospectively for one year or until death. Clinical events and usage of antibiotics were recorded. In patients with asymptomatic bacteriuria, repeated urine cultures were obtained every two months. RESULTS: Eighty-five (43.3%) of a total of 196 elder residents screened presented asymptomatic bacteriuria. There were no differences between patients with and without asymptomatic bacteriuria in age, gender, and underlying diseases. Patients with asymptomatic bacteriuria were significantly more bed-ridden (91.7% vs. 82.1%, P = 0.05); demented (78.8% vs. 59.8%, P = 0.03); and incontinent of urine (93% vs. 71.4%, P < 0.0001) and bowel (85.8% vs. 59.3%). During one year of prospective observation, bacteriuric patients had a mortality rate of 25.9%, compared to 7.1% for nonbacteriuric (P < 0.0001). Mortality in the group with bacteriuria was higher due to both urinary infection and other causes. CONCLUSIONS: In our population, asymptomatic bacteriuria was associated with increased functional impairment and increased mortality over 12 months. The increased mortality, however, was not fully attributable to urinary infection.

Journal Article↗

Seroprevalence of antibodies against Toxoplasma gondii among recently immigrating Ethiopian Jews.

Sera from 144 Ethiopian immigrants who arrived in Operation Solomon, 1991, living in three absorption centers in the Jezreel Valley were tested for antibodies against Toxoplasma gondii. Antibodies were found in 34% of the test group, with a rise in prevalence with age from 0% in the first decade to 46% in the > 40 age-groups. The prevalence in the Ethiopians was higher than in Jewish kibbutz members (22.8%) and lower than in Arab villagers (55.8%). During the reproductive years (age 20-39) the rate of seroconversion is 1% per year, and screening of pregnant Ethiopian women for antibodies to T. gondii should be considered.

Adolescent↗

Prevalence of markers of infection with hepatitis B and C viruses in immigrants of operation Solomon, 1991.

Sera of 200 recent Ethiopian immigrants (less than 1 year in Israel) were tested for the presence of antibodies against hepatitis B and hepatitis C viruses. The prevalence of the various markers was: anti-hepatitis B core antigen (anti-HBc) 52%, and hepatitis B surface antigen (HBsAg) 11.5%. None of the HBs-positive sera tested positive for IgM-anti core. Sixty-eight sera from nonvaccinated subjects were tested for anti-HBs, and 12 of them were anti-HBc negative/anti-HBs positive (the only positive marker was anti-HBs). Four of 23 HBsAg-positive sera were HBcAg positive (17%), and only 1 of 18 HBeAg-negative sera was positive for anti-e antibodies. Antibodies to hepatitis C were positive in 6/200 sera (3%).

Adolescent↗