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R Rao

Publications and source records attributed to R Rao.

251 records · Page 14Linked to original sources
PubMedDate not supplied

Malignant oncocytoma of the nasal cavity: a case report.

Malignant oncocytoma is a rare clinical entity and is most commonly seen in the salivary glands. Its occurrence in the nasal cavity is extremely rare, and only 4 such cases have been reported in the literature. The authors report one such case in a 60-year-old woman, which presented as a slow-growing nasal mass arising from the nasal septum, with no lymph node metastasis, which was successfully managed by a combined modality of treatment-surgery followed by radiation therapy. The relevant literature has been reviewed. The case is discussed as a possible differential diagnosis for a mass in the nose.

Adenoma, Oxyphilic↗
PubMedDate not supplied

meso-Aryl smaragdyrins: novel anion and metal receptors.

An easy synthesis of core-modified meso-aryl smaragdyrins containing oxygen and sulfur in addition to pyrrole nitrogens has been achieved through an alpha-alpha coupling involving modified tripyrrane and dipyrromethane. The complexation behavior of these macrocycles toward anions (Cl-, F-, AMP-) and metal cations (Rh(I), Ni(II)) is reported. Specifically, it has been shown that the Rh(I) and Ni(II) ions bind to the smaragdyrin skeleton in its free base form. X-ray structural studies of Rh(I) complex 1 indicate an eta 2-type coordination involving only one imino and one amino nitrogen of the dipyrromethane unit. However, all four bipyrrole nitrogens participate in the coordination with the Ni(II) ion. Furthermore, Ni(II) coordination oxidizes the ligand, and the complex is formulated as the pi-cation radical of nickel(II) smaragdyrin. The anion complexation is followed in both the solid and solution phases. Solution studies reveal that the binding constants of the ions with the protonated form of smaragdyrin vary as F- > AMP- > Cl-. The X-ray structure of the chloride anion complex reveals that the chloride ion is bound above the cavity of the smaragdyrin macrocycle through three N-H...Cl hydrogen bonds. Crystal data with Mo K alpha (lambda = 0.710,73 A) are as follows: 1, C41H27N4O3Rh, a = 11.836(8) A, b = 12.495(9) A, c = 12.670(2) A, alpha = 69.09(6) degrees, beta = 78.78(6) degrees, gamma = 77.02(5) degrees, V = 1692.1(17) A3, Z = 2, triclinic, space group P-1, R1 (all data) = 0.0471; 4.HCl, C41H29N4O1Cl, a = 11.878(2) A, b = 17.379(4) A, c = 16.015(3) A, beta = 109.546(10) degrees, V = 3115.47(11) A3, Z = 4, monoclinic, space group P2(1)/c, R1(all data) = 0.0850.

Journal Article↗
PubMedDate not supplied

Pebbling of the skin: a marker of Hunter's syndrome.

A 9-year-old boy, the third child of nonconsanguinous parents, presented with asymptomatic, solid, raised skin lesions over the upper back. They first appeared at the age of 4 years. Gradually similar lesions appeared over the chest, neck, arms, and thighs. On examination, he had firm, hypopigmented to skin-colored papules and nodules which coalesced to form ridges in a reticular pattern (pebbling of the skin) and were arranged bilaterally and symmetrically over the scapulae, pectoral region of the chest, and lateral aspects of the arms and thighs. They resembled sulci and gyri of the brain. He had normal intelligence, short stature, coarse facial features, thick lips, a large tongue, clear corneas, a protuberant abdomen with hepatosplenomegaly, and broad hands with clawlike contractures of the distal interphalangeal joints. Investigations revealed cardiomegaly and proximal tapering of metacarpal bones. Although peripheral blood smear and urine spot test for mucopolysaccharides were negative, histopathology of a representative skin lesion was compatible with the diagnosis of Hunter's syndrome. The case is reported for its rarity and the typical skin lesions, the recognition of which may be helpful in diagnosis and genetic counseling.

Child↗
PubMedDate not supplied

Screening tests for the detection of bladder cancer.

Eighty-one individuals had urine cytologies, urinary carcinoembryonic antigen (CEA) determinations and urinary immunoglobulin levels performed in an effort to evaluate various screening tests for the diagnosis of bladder cancer. Urinary cytologies had a predictive value of 57% in detecting bladder cancer. Urinary CEA was of little value in detecting vesical malignancy. Urinary immunoglobulins, particularly IgG and IgA were significantly elevated in the presence of bladder cancer.

Carcinoembryonic Antigen↗