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Biomedical subjects

R R Steinman

Publications and source records attributed to R R Steinman.

29 records · Page 2Linked to original sources
PubMedDate not supplied

Effect of infusing selected chemical compounds on dentinal fluid movement in the rat.

Intra-arterial infusion of carbamyl phosphate or of carbamyl-DL-aspartic acid into rats on a cariogenic diet greatly stimulated the movement of fluid through the odontoblastic processes. The infusion of sodium cyanate also stimulated fluid movement. Guanidine HCL and L-asparagine were active at higher concentrations. Purifying the urea on a mixed-bed ion exchange resin virtually removed its stimulatory effect on dentinal fluid movement. The action of urea is apparently attributable to contamination with sodium cyanate.

Acriflavine↗
PubMedDate not supplied

Effect of selected dietary additives on the incidence of dental caries in the rat.

Weanling rats fed a cariogenic diet supplemented with carbamyl phosphate, in combination with egg shell meal and trace elements, showed a striking reduction in the incidence of caries. The cariostatic efficacy of carbamyl phosphate is significant because it stimulates fluid movement within odontoblasts via the hypothalamic-parotid gland endocrine axis.

Animals↗
PubMedDate not supplied

Acidogenic potential of cariogenic and noncariogenic diets in the rat.

No significant difference in lactic acid content was observed in dood residues removed from the occlusal grooves of rats receiving Purina lab chow or the 62% sucrose cariogenic diet. The incubation of rat saliva with Purina chow, with 62% sucrose diet, or with the 62% sucrose diet supplemented with carbamyl phosphate, egg shell meal, and the trace elements zinc, molybdenum, and chromium produced in 24 hours essentially the same pH surve. The terminaltitratable acidity observed in saliva incubated with the 62% unsupplemented diet, however, was significantly less than that produced in salivary mixtures containing either Purina chow or supplemented sucrose diets.

Animal Feed↗