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Biomedical subjects

R R Monroe

Publications and source records attributed to R R Monroe.

At least 19 recordsLinked to original sources
PubMed1991

TV and ECT.

Explore the source record for details and available documents.

Depressive Disorder↗
PubMed1991

Maintenance electroconvulsive therapy.

Maintenance electroconvulsive therapy remains an infrequently used and insufficiently researched treatment for the prevention of relapse and recurrence of affective illnesses. The foundation for this treatment is examined by reviewing the relevant scientific literature, with particular attention to identifying those patients who may benefit most from this form of therapy, as well as establishing standard techniques of application. A critical assessment of current research is made, and areas for future investigation are proposed.

Electroconvulsive Therapy↗
PubMed1982

DSM-III style diagnoses of the episodic disorders.

The episodic disorders can be clearly differentiated from schizophrenia as now rigorously defined in Diagnostic and Statistical Manual of Mental Disorders, 3rd Edition. Because the affective disorder is a more heterogeneous one, the boundaries between this group and episodic disorders is less precise, but this boundary could be clarified with a rigorous definition of the affective disorders comparable to that utilized for schizophrenia. The acute mode of onset and the remitting course are the most useful differentiating features between schizophrenia and the episodic disorder. The presence of toxic or other organic symptoms, including clouding of sensorium, illusions, visual hallucinations, formes frustes of epilepsy, childhood history of minimal brain dysfunction or attentional deficits, and soft neurological signs, aid in differentiating the episodic disorders from manic and depressive episodes. There is a subgroup of episodic disorders that can be differentiated from the epileptoid or organic episodic disorders as well as from the major psychoses by psychodynamic factors alone.

Attention Deficit Disorder with Hyperactivity↗
PubMed1975

Anticonvulsants in the treatment of aggression.

A significant number of violent acts are committed by individuals in whom central nervous system instability can be demonstrated by special electroencephalographic (EEG) activation procedures utilizing alpha-chloralose as the activating agent. Furthermore, subcortical electrograms suggest that this instability is related to a circumscribed ictal phenomenon in the limbic system. The abruptness of the aggressive act, the fact that the behavior is so often out of character for the individual and inappropriate for the situation, as well as the confusion and partial amnesia which accompany these episodes lend clinical support for the ictal hypothesis. Some anticonvulsants not only block the activated abnormalities on the EEG but also lead to dramatic clinical improvement in those individuals showing repeated and frequent aggressive behavior. For instance, in one study 46.7 percent and 53.3 per cent of the patients demonstrated activated abnormalities on no drug and placebo, respectively. When these same patients were receiving chlorpormazine or trifluoperazine, the activation rates were 60.0 per cent and 73.3 per cent, respectively. On the other hand, when these same patients were placed on a regimen of chlordiazepoxide the activation rate was reduced to 20 per cent (p smaller than or equal to .01). Another study involved severely distrubed chronically hospitalized psychotic patients whose aggressive uncontrolled outbursts relegated then not only to a locked ward, but often to isolation rooms despite high doses of phenothiazines. A regimen of chlordiazepoxide and

Adult↗