Biomedical subjects
Publications and source records attributed to R R Lukin.
Two cases of neurofibromatosis and intracranial arterial occlusive disease are reported. The radiographic and clinical features of these and twelve previously reported cases are reivewed.
Two giant thrombosed aneurysms of the middle cerebral artery are reported with a review of the pertinent literature. A tortuous channel through the thrombus results in an unusual and characteristic angiogram. Mechanisms involved in the formation of this lesion are discussed.
Central nervous system sarcoidosis and its varied neuroradiological manifestations are reviewed. Two cases of mechanical obstruction secondary to sarcoid granulomata at the outlet of the fourth ventricle are described.
A case of traumatic thrombosis of the left subclavian and left vertebral arteries is reported which presented with signs of basilar artery insufficiency and right homonymous hemianopsia 3 weeks after the injury. The diagnosis, which was clinically unsuspected, was made by angiography. Surgical removal of the thrombus was successful.
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The authors' experience using the Debrun detachable balloon catheter system in occluding surgically-created carotid-jugular fistulas is described. Useful technical points in preparing and using the system are outlined. Technical failures were encountered both in creation of the fistula model and in use of the system, and their occurrence is documented. It is concluded that, when familiarization with the system's operation is attained, the detachable balloon catheter system promises to offer a valuable method of treatment of traumatic carotid-cavernous fistulas in humans.
A patient presented 12 h following trauma with a slowly expanding neck mass. Both CT and sialographic evaluation demonstrated a fracture of the left submandibular gland.
The characteristics of various types of collimators have been studied systematically for the EMI Mark I brain scanner. The degree of collimation ranged from the 13-mm adjacent A and B slices to 3-mm separated slices. Multiple phantom studies (including variable density immiscible liquid interfaces) have been performed to evaluate the effect of collimation on (a) the line-spread function, (b) the change in effective absorption number, and (c) volume averaging. Effects associated with the technique settings involving the kVp, the mA, and the scan time were also investigated. The results of TLD dose measurements as a function of collimation are presented. The significance of collimation in specific clinical studies involving small, fairly well-circumscribed lesions is discussed.
The aim of this report is to describe the intracranial cerebrovascular abnormalities and clinical status of 8 children who had familial lipoprotein disorders and evidence of thromboembolic cerebrovascular disease. Six of the 8 children had low levels of plasma high density lipoprotein cholesterol, two had high triglyceride levels, and all came from kindreds characterized by familial lipoprotein abnormalities and premature cardio- and/or cerebrovascular atherosclerosis. Vascular occlusion, irregularities of the arterial lumen, beading, tortuosity, and evidence of collateralization were consistently noted. We speculate that cerebrovascular arteriosclerosis in pediatric ischemic stroke victims who have familial lipoprotein abnormalities may be related to lipoprotein-mediated endothelial damage and thrombosis formation, or to the failure to restore endothelial cells' integrity following damage. The apparent association of lipoproteins and strokes in children and their families merits further exploration, particularly when assessing cerebral angiograms in pediatric ischemic stroke victims. In children with unexplained ischemic cerebrovascular accidents, the diagnostic possibility of occlusive arteriosclerosis with thrombosis must be entertained.
Using seven illustrative cases, the authors discuss the computerized tomographic (CT) appearance of cranial epidermoid tumors. These tumors are of low density (-2 to +10 EMI units), seldom show calcification, and do not enhance with contrast medium. Their differentiation from dermoid tumors and craniopharyngiomas is also discussed.
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