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Biomedical subjects

R R Jacobs

Publications and source records attributed to R R Jacobs.

94 records · Page 6Linked to original sources

Reduction, stability, and strength provided by internal fixation systems for thoracolumbar spinal injuries.

Anterior, posterior, and combined thoracolumbar spinal injuries were simulated in human cadaver specimens and then stressed in flexion, before and after stabilization, with Weiss Springs, Roy-Camille plates, vertebral body plates, and Harrington compression and distraction rods. The reduction, stability, and strength were determined for each implant-injury combination. For posterior ligamentous injuries, the Harrington compression system on the laminae gave reduction in extension, stability to that of the intact spine, and failure at 87.6 Nm bending load with 14.1 J energy absorption. For anterior vertebral body fracture, Harrington distraction rods from three vertebrae above to three below the injury gave a reduction in extension with stability similar to that of the intact spine. Failure occurred at 81.6 Nm load, one-third greater than with rods two levels above to two below, and 14.0 J energy absorption, twice that for the short rod. The more unstable combined anterior and posterior injury was satisfactorily reduced only by the long distraction system, which failed at 44.1 Nm load, twice that for the short rod, and 5.7 J energy absorption. By accurately determining what structures have been injured, and appropriate fixation device can be selected and the strength of the stabilized spine estimated. A thorough understanding of the biomechanics of the spine is essential for successful clinical utilization of these experimental data.

Aged↗

Methylprednisolone in posttraumatic pulmonary insufficiency.

The effect of methylprednisolone, 30 mg/kg on the musculoskeletal trauma model in dogs were compared with the previously reported untreated models. The atelectasis, inflammation, and alveolar membrane thickening were ameliorated. There was a decrease in the coagulopathy of trauma as well as increased cardiac output, pulmonary vasodilitation and a decrease in the pulmonary shunt. Although these changes are salutory, the majority of patients with posttraumatic pulmonary insufficiency can be adequately treated by prompt adequate volume replacement, blood replacement, and appropriate use of cardiotonic drugs. Only in the resistant patient are steroids necessary.

Animals↗

Internal fixation of intertrochanteric hip fractures: a clinical and biomechanical study.

One hundred seventy-three cases of intertrochanteric fractures treated by internal fixation are reviewed: 72 treated with the Jewett nail and 101 with the Richards compression hip screw. Both devices maintained adequate reduction in the majority of cases. Treatment failure: loss of fixation, symptomatic joint penetration, aseptic necrosis, malunion and nonunion occurred in 25% of the Jewett nail cases and 6% of the Richards screw cases. In vitro biomechanical studies demonstrate that the compression screw is subjected to less bending stress by acting as a lateral "tension band" in stable reductions and by allowing sliding, thus shortening the bending movement lever arm in unstable reductions. The compression hip screw is valuable in the treatment of intertrochanteric hip fractures. In stable conditions, it acts as a tension band producing more force transmission through the medial cortex, stressing the implant more in tension and less in bending. In unstable conditions with higher shearing forces, the device will shorten the lever arm, decreasing the bending moment, as well as avoiding penetration of the femoral head.

Biomechanical Phenomena↗

Thoracolumbar spinal injuries. A comparative study of recumbent and operative treatment in 100 patients.

Internal fixation of fractures of the thoracolumbar spine with early ambulation is evaluated in this study of 100 patients with 106 fractures, 34 of which were treated by recumbency, 13 with Meurig-Williams plates, and 59 with Harrington rods. Fracture reduction in the recumbent group was 14% unsatisfactory and 82% satisfactory; only one fracture was anatomically reduced. After plating, 38% of fracture reductions were unsatisfactory and 61% satisfactory. Harrington rod reduction and internal fixation resulted in 67% anatomic, 31% satisfactory, and 2% unsatisfactory reductions. Neurologic improvement in partial lesions was 53% with Harrington rods and 44% with recumbent treatment. For paraplegic patients the time between treatment and wheelchair mobilization was reduced from 10.5 weeks with recumbent treatment to 5.3 weeks with Harrington instrumentation. Rehabilitation time for ambulatory candidates was decreased from 7.1 weeks to 2.5 weeks. Complications were reduced from 18% in the recumbent group to 7% in the Harrington rod groups. By using the three above-three below, rod long/fuse short approach rather than the two above-two below with fusion over the length of the rods technique, the number of anatomic reductions was increased from 70% to 82% and the length of the fusion decreased from 4.8 levels to 1.4 levels.

Adolescent↗