Pulmonary microscopic and ultrastructural effects of femur fracture and 15% hemorrhage in dogs.
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Biomedical subjects
Publications and source records attributed to R R Jacobs.
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In considering intravenous injection of lipid as a model of fat embolism, contamination is frequent and purity must be demonstrated. Musculoskeletal trauma causes mild arterial hypoxia whereas intravenous pure triolein 0.1 mg/kg does not. Trauma produced a leukocytosis and elevated sedimentation rate not found in the lipid injected dogs. Evidence for consumptive coagulopathy was found in the trauma group but only a mild thrombocytopenia resulted from intravenous triolein. The traumatized dogs demonstrated an increase in the triglyceride level, an increase in the cholesterol phopholipid ratio and an increase in the cholesterol containing beta and prebeta lipoprotein fractions, all of which could lead to formation of pulmonary fat emboli containing cholesterol.
This report reviews the outcome of surgery for back pain in 50 patients who had had previous back surgery. All were treated by exploration and posterolateral fusion of the spine. Those with nerve root irritation had thorough nerve root decompression including wide laminectomy when needed. Back pain was relieved in 44 of 50 patients, and sciatic pain was relieved in 38 or 43 patients. Postoperative functional activity (return to work) was regained in 24 of the 30 patients in whom this could be assessed. In six patients with back pain and in five patients with sciatic pain surgical benefits were insignificant; these were rated as poor results. In six patients the rehabilitation goal of satisfactory level of activity was not achieved.
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