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Biomedical subjects

R R Bailey

Publications and source records attributed to R R Bailey.

At least 271 records · Page 15Linked to original sources
PubMed1977

Water-logged women--idiopathic oedema.

The clinical details of ten women with idiopathic oedema are presented and one is discussed in detail. The condition is characterised by an excessive diurnal weight gain with the development of peripheral oedema when the patient is in the upright position. Treatment is frequently unsatisfactory but should include, a full explanation, weight reduction, moderate sodium restriction, psychiatric assessment, no smoking and avoidance of prolonged standing. If this approach fails the smallest effective dose of a mild diuretic agent may be prescribed during an episode of fluid retention.

Adolescent↗
PubMed1977

Treatment of urinary-tract infection with a single dose of amoxycillin.

31 patients with a urinary infection were treated with a single oral dose (3 g for adults and 100 mg/kg for children) of amoxycillin; 23 (74%) were cured. 20 women and 26 children were then randomly allocated to either a single dose of amoxycillin of a 5- to 7-day conventional course of the same antibiotic. The results of both treatment regimens were comparable. Single-dose therapy for the treatment of urinary-tract infections was simple, effective and well tolerated. Patients preferred taking their treatment in this manner. Failure of single-dose therapy to eradicate bacteriuria may indicate which patients require subsequent investigations of their urinary tract.

Administration, Oral↗
PubMed1977

Intravenous co-trimoxazole ("Bactrim") in the treatment of acute pyelonephritis.

Patients with acute pyelonephritis may be extremely ill and have a complicating septicaemia. This may necessitate the parenteral administration of an appropriate antibacterial agent. This paper reports the use of intravenous co-trimoxazole in two young women with severe acute pyelonephritis. 101 ml of co-trimoxazole (800 mg sulphamethoxazole and 160 mg trimethoprim) was added to 500 ml of 5% dextrose in water and infused over a 90-min period. This treatment was given every 12 h for five doses, before switching to oral co-trimoxazole. The treatment was clinically and bacteriologically successful and no side effects were noted.

Acute Disease↗
PubMed1977

Management of cystitis in young women.

The common clinical problem of recurrent symptomatic urinary tract infections (UTI) in young women may be inconvenient and distressing to both the patient and her family, particularly if the infections are not managed in a rational manner. A suggested approach is included in table 1.

Anti-Bacterial Agents↗
PubMed1976

Prazosin in the treatment of patients with hypertension and renal functional impairment.

Prazosin was used as an additional antihypertensive agent for treating 16 patients with hypertension and significant renal functional impairment. The drug was effective in 13 patients at a mean daily dose of 7.9 mg. The most important side effect of prazosin treatment was dizziness which occurred on standing or following exertion, and was seen either after the first dose or following a large increase in dose. This could be prevented by giving the very first dose of 0.5 mg late in the evening. Five patients complained of palpitations. In no patient was there a deterioration in renal function which could be attributed to prazosin. Five women had a significant improvement in renal function.

Female↗
PubMed1976

Tobramycin in the treatment of severe and complicated urinary tract infections.

Tobramycin is a new aminoglycoside antibiotic with pharmacological similarities to gentamicin. Eleven of 15 patients with a severe or complicated gram-negative urinary tract infection were cured by treatment with a five day course of tobramycin. No side effects were noted. This drug should prove beneficial for the treatment of severe gram-negative sepsis and promises to be particularly valuable for infections due to Pseudomonas aeruginosa and organisms resistant to gentamicin.

Adult↗
PubMed1976

Deterioration in renal function in association with co-trimoxazole therapy.

Deterioration in renal function has been observed in four patients who were taking co-trimoxazole. Three patients had stable chronic renal failure, and in two of these there was a further permanent impairment of renal function. The remaining patient received co-trimoxazole while recovering from a short episode of acute oliguric renal failure. It is suggested that co-trimoxazole be withheld, or used with caution in patients with impaired renal function.

Acute Kidney Injury↗
PubMed1976

What the urine contains following athletic competition.

Forty-two of 369 athletes were found to have a positive Occultest on the first urine sample voided following athletic competition. This positive reaction could be due to the presence of either myoglobin or haemoglobin. The Occultest was most often positive in competitors in the longer duration events such as the marathon. Twenty-six of these 42 specimens with a positive Occultest contained over 10 red cells per mm3. The urine samples were also examined for white cells, casts, bacteriuria and the concentration of urea, creatinine, electrolytes and protein. Proteinuria was a frequent finding and increased with the severity of the exertion.

Bacteriuria↗
PubMed1976

IgA nephropathy: a report on three cases.

Three cases are presented of a recently defined group of patients with renal disease who presented with macroscopic or persisted microscopic haematuria. These patients were found to have deposition of IgA in the glomerulus. They may thus be classified as suffering from an immunologically related glomerulonephritis.

Adult↗