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Biomedical subjects

R Pini

Publications and source records attributed to R Pini.

64 records · Page 4Linked to original sources
PubMed1978

[Hemodynamic classification of acute myocardial infarction: physiopathological aspects and prognostic implications. Considerations on 130 cases (author's transl)].

Hemodynamic evaluations of 130 patients with acute myocardial infarction were performed by right and/or left heart catheterization. 115 patients were subdivided in six groups by the pulmonary artery mean pressure (PMP)-left ventricular stroke work index (LVSWI) relationship: 1) normal LVSWI in relation to PMP (14.8% of all cases); 2) increased LVSWI in relation to PMP (0.9%); 3) moderately reduced LVSWI with increased PMP (severe heart failure-cardiogenic shock) (7.0%); 5) reduced LVSWI with low or normal PMP (22.6%); 6) normal LVSWI with elevated PMP (reduced left ventricular compliance or high pulmonary vascular resistance) (15.7%). 28 cases were studied by right and left heart catheterization; in 10 cases only left heart catheterization was performed. Discriminant analysis on the values measured at the first stage of hemodynamic monitoring was conducted: this type of mathematical analysis seemed to provide a more useful prognostic index.

Acute Disease↗
PubMed1977

[Infusion of plasma volume expanders in the evaluation of left ventricular function (author's transl)].

39 patients, subdivided in four groups [I) previous myocardial infarction; II) ischaemic heart disease; III) hypertension; IV) cerebrovascular disease] were administered i.v. low molecular weight dextran in the course of right heart catheterization. The curves of the left ventricular function were determined by the LVSWI-LVFP relationship measured before the test, after the first 150 ml of dextran infusion, at the point of maximal increase of the LVSWI, and at the end of the infusion. The initial values of the LVSWI and SV were lower in the first group with respect to the other three (P less than 0.001), not significantly unlike those of the LVFP. During dextran infusion it is possible to observe an increase of the LVFP in all four groups (P less than 0.01), and of the SV (P less than 0.02) and LVSWI (P less than 0.01 and P less than 0.05, respectively) in the first and the third groups. At the end of the test, different values of the LVSWI (P less than 0.001) and the LVFP (P less than 0.01) were observed in the four groups. The calculated deltaSI/deltaLVFP indices were not significantly different in the four groups, whereas a P less than 0.001 was obtained for the values of the deltaV/deltaLVFP indices (56, 67, 73 and 138 ml/mmHg for the groups I, II, III and IV, respectively). Dextran infusion proved to be a useful test for the hemodynamic assessment of different cardiovascular diseases.

Adult↗
PubMed1977

[Left ventricular microcatheterization during acute myocardial infarction (author's transl)].

Left ventricular microcatheterization at the bedside was accomplished in 20 acutely ill patients with myocardial infarction. Direct measure of the left ventricular end-diastolic pressure shows that its values can substantially differ from those of the pulmonary artery end-diastolic pressure. The authors observed that left ventricular microcatheterization is indicated, in the course of acute myocardial infarction, in the following circumstances: --when either the pulmonary artery end-diastolic or the pulmonary capillary pressure is beyond normal limits; --in the presence of tachyarrhythmias which, for alteration of the dynamics of atrial contraction, increase the difference between the left ventricular and pulmonary artery end-diastolic pressures; --when a mitralic defect is associated with the acute myocardial infarction.

Acute Disease↗
PubMedDate not supplied

Acoustic transients following excimer laser ablation of the cornea.

Pressure transients occurring inside the eyeball as a consequence of excimer laser ablation of the cornea were measured at various distances along the optical axis, on enucleated porcine eyes. Positive (compressive) pressure spikes up to 90 bars were observed, lasting 100 ns, and developing, as they propagated in the eyeball, satellite rarefaction pulses with negative pressure as high as -40 bar. Such rarefaction wavefronts can trigger the formation of cavitation bubbles, in both the anterior and posterior chamber, depending on the ablation geometry. The potential risks associated with these photoacoustic phenomena, particularly for retina and corneal endothelium, are outlined.

Acoustics↗