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Biomedical subjects

R Pies

Publications and source records attributed to R Pies.

49 records · Page 3Linked to original sources
PubMed1983

Geriatric psychopharmacology.

When selecting a psychotropic agent for an elderly patient, the physician must consider such factors as impaired renal and hepatic metabolism, decreased protein-binding of drugs and increased central nervous system sensitivity. Accordingly, compounds should be selected on the basis of their pharmacokinetic and side-effect profiles. High-potency antipsychotics, because of their lower degree of anticholinergic activity, are usually preferable to the low-potency agents. Cardiac toxicity is an important consideration in selecting an antidepressant.

Aged↗
PubMed1983

Is paradoxical intention risk-free?: a review and case report.

Paradoxical interventions are used in treating a wide variety of psychiatric disorders. Although published reports create the impression of almost uniform success, a survey of the literature reveals that most studies lack appropriate controls, rely solely on patients' self-reports, and are complicated by ancillary treatment. To further demonstrate that the treatment may not be as risk-free as the literature implies, the adverse effects produced in a patient with borderline personality disorder are described.

Adult↗
PubMed1982

Easy to be hard.

Explore the source record for details and available documents.

Humans↗
PubMed1981

Persistent bipolar illness after steroid administration.

A 28-year-old woman received a single course of corticosteroids for treatment of ulcerative colitis. She subsequently became depressed; shortly thereafter, signs of mania developed. Despite discontinuation of corticosteroid therapy, the patient has had five bouts of mania, closely followed by severe depression, in the past 1 1/2 years. This seems to be the first case of persistent bipolar illness after exogenous steroid administration.

Adult↗
PubMed1979

On myths and countermyths: more on Szaszian fallacies.

There has never been a single set of criteria for the ascription of disease. The pathoanatomic view ascribed to Virchow and propounded by Thomas Szasz has coexisted with the patient-centered or phenomenologic view for millenia. Schizophrenia, as well as such entities as idiopathic epilepsy and migraine, may be considered a disease because it entails suffering and incapacity, albeit in the absence of any obvious lesion. The Szaszian view of disease neither appreciates the nuances of Virchow's own position nor acknowledges the fluidity of current medical nosology.

Europe↗