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Biomedical subjects

R P Phillips

Publications and source records attributed to R P Phillips.

23 records · Page 2Linked to original sources
PubMed1990

Steroid induced glaucoma: a report of two cases with a review of morbidity and prescribing in general practice.

An eight-week general practice based prospective study was carried out to determine the incidence and prevalence of various eye conditions and the frequency of prescription of different topical eye preparations. The most frequently diagnosed eye conditions were infectious conjunctivitis (35%), glaucoma (16%), allergic conjunctivitis (11%), and keratoconjunctivitis sicca (9%). Betamethasone was the fourth most commonly prescribed preparation (9%). Eye preparations containing steroids accounted for 14% of prescriptions. Two cases of steroid induced glaucoma are presented as an illustration of the potential hazards of these preparations. The pathogenesis of steroid induced glaucoma is discussed.

Administration, Topical↗
PubMed1985

Influence of rectal washout on bacterial counts in the rectal stump.

Forty-three patients undergoing a restorative colorectal resection were randomized to have their rectal stump washed out with either 0.9 per cent saline, 2.5 per cent povidone-iodine or 0.3 per cent sodium hypochlorite. The bacterial counts before and after washout for Escherichia coli and Bacteroides fragilis were compared using the Mann-Whitney U test. There was no significant difference in the counts for E. coli before and after washout with saline (log 9.7-log 9.7 organisms/ml) and saline had no influence on the counts of B. fragilis (log 7.9-log 6.5 organisms/ml). Hypochlorite was associated with a significant reduction in E. coli counts (log 6.1-log 1.1 organisms/ml, P less than 0.005) and the counts of B. fragilis (log 8.1-log 0.0 organisms/ml, P less than 0.005). The counts of B. fragilis were significantly reduced by povidone-iodine (log 8.1-log 1.1 organisms/ml, P less than 0.005) but there was no significant reduction in counts of E. coli (log 5.6-log 5.3 organisms/ml). The data suggest that sodium hypochlorite is better than povidone-iodine or saline as a rectal washout for colorectal anastomosis.

Bacteroides fragilis↗
PubMedDate not supplied

A high capacity transcutaneous energy transmission system.

A transcutaneous energy transmission system is described that transmits up to 60 W for use by a mechanical circulatory support system or other internal device. It contains an input power conditioning circuit that permits it to sustain the required output with input voltages ranging from 10 to 16 V. The transcutaneous energy transmission system demonstrated a best overall efficiency of 77% when connected to a resistive load and 74% when connected to a mechanical circulatory support system pumping up to 8.0 L/min to a mock circulation system. These figures included the losses in the conditioning circuit, which, when operated separately, had an efficiency of 94%. By tuning the resonant frequency of the primary, an output with only a 10% variation was achieved with coils separated by between 0 and 25 mm. A model of the inductively coupled resonant circuits was analyzed and a closed form solution obtained that verified the equations reported by Galbraith et al. Additional useful results obtained included an expression for the efficiency of the power transfer through the coupled circuits and the ratio of the current circulating in the primary and secondary coils. These results indicate that information useful for control of the output voltage of the secondary may be available in the primary circuit.

Assisted Circulation↗
PubMedDate not supplied

Bilateral anterior ischaemic optic neuropathy due to optic disc drusen.

PURPOSE: To report a case of bilateral anterior ischaemic optic neuropathy due to buried optic disc drusen. METHODS: Case report. RESULTS: A 64-year-old man presented with swollen optic discs and features suggestive of anterior ischaemic optic neuropathy (AION) in the left and right eye on two separate occasions ten months apart. Detailed ocular examination at presentation and systemic investigations did not reveal an underlying cause for the AION. At a later follow-up, optic disc drusen were noted in both eyes as partial optic atrophy had set in. This was confirmed by ultrasound B scan and demonstration of autofluorescence. CONCLUSIONS: In patients presenting with AION uncommon underlying causes must be considered. Routine ultrasound B scan at presentation can easily establish or exclude optic disc drusen as an underlying cause.

Fluorescein Angiography↗