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Biomedical subjects

R P Mathur

Publications and source records attributed to R P Mathur.

35 records · Page 2Linked to original sources
PubMed1981

Evaluation of brodifacoum against T. indica, M. hurrianae and R. rattus.

Brodifacoum was evaluated in the laboratory against the two gerbils, Tatera indica and Meriones hurrianae and the house rat, Rattus rattus. The acute oral LD50 for these rodents was found to be 0.10 mg/kg, 0.083 mg/kg and 0.77 mg/kg respectively. Feeding tests with 0.002% and 0.005% brodifacoum produced a 100% mortality after a 3-day feeding period in the gerbils and after a 4-day period in R. rattus. The anticoagulant is toxic at both the concentrations to all three species but is less palatable in comparison to plain baits. Results of this laboratory evaluation indicates that 0.002% brodifacoum-treated bait can be effectively used against T. indica, M. hurrianae and R. rattus.

4-Hydroxycoumarins↗
PubMed1980

Laboratory evaluation of anticoagulant-treated baits for control of the northern palm squirrel, Funambulus pennanti Wroughton.

Individually caged northern palm squirrels, Funambulus pennanti, were fed with bait containing 0.025% warfarin or fumarin, 0.0075% chlorophacinone or 0.005% brodifacoum for a fixed number of days varying from 1 to 14. Brodifacoum (WBA 8119) was found most toxic since 66% and 70% of the animals died after one and two days' feeding respectively. Chlorophacinone killed 70% of the squirrels after three days' feeding. Squirrels were relatively tolerant to warfarin and fumarin since the mortality after a period of 14 days' feeding was only 58% and 75% respectively.

Animals↗
PubMedDate not supplied

Parameters affecting the decay of some organophosphorus pesticides: a study by high-performance liquid chromatography.

An HPLC procedure has been developed to follow the decay of malathion and methylparathion under control conditions using an mu-Bondapak C18 column with a mixture of acetonitrile and water to mobile phase and an ultraviolet detector for detection. Studies have been conducted to monitor their degradation in water and soil at different temperatures, pH and organic content. The results show that the persistence of the pesticides decreases with increase in temperature, pH and organic content.

Acetonitriles↗
PubMedDate not supplied

Accumulation pattern of pesticides in tropical fresh waters.

High-performance liquid chromatography has been used to study the persistence of commonly used organophosphorus and carbamate pesticides-carbaryl, carbendazim, carbofuran, dimethoate, malathion and methyl parathion in river water in the presence of bottom sediment in laboratory aquaria. The fate of pesticides in water and sediment in pre- and post-monsoon water from three sources has been compared. It has been established that rapid degradation occurs once the pesticide leaches into sediment from water. Degradation was at a much faster rate in post-monsoon water and sediment. It was found that pH and organic matter content affect rate of decay.

Antinematodal Agents↗
PubMedDate not supplied

Identification of metabolites of malathion in plant, water and soil by GC-MS.

Metabolism of malathion (O,O,-dimethyl S-[1,2-bis(ethoxy carbonyl)-ethyl]phosphorodithioate) has been studied in plants, water and soil. A number of products identified by gas chromatography-mass spectrometry (GC-MS), have been formed by de-esterification, oxidation and hydrolysis of malathion. Hydrolysis of the P-S and C-S bonds occur in alkaline pH 8.0 and acidic pH 5.5, respectively.

Brassica↗
PubMedDate not supplied

Simultaneous determination of a mixture of organophosphorus and carbamate pesticides by high performance liquid chromatography.

A simple HPLC procedure has been developed for the simultaneous determination of a mixture of standard carbaryl, carbofuran, carbendazim, dimethoate, malathion and methyl parathion from a spiked agricultural soil sample. The pesticide mixture has been extracted using methanol-water. A concave gradient elution with acetonitrile-phosphate buffer for 15 min followed by linear elution for 5 min, using a wavelength of 224 nm for detection, has been found to resolve the mixture efficiently.

Benzimidazoles↗
PubMedDate not supplied

Degradation of organophosphorus and carbamate pesticides in soils--HPLC determination.

Best conditions suited for the extraction and trace analysis of dimethoate, malathion, methyl-parathion, carbaryl, carbendazim and carbofuran in soils, using HPLC, were established. This was followed by studies related to persistence of residues in different soils. Half-life and time taken for 95% dissipation were determined in each case. Higher pH, moderate moisture and high calcium carbonate content aided degradation while organic matter increased persistence.

Biodegradation, Environmental↗
PubMedDate not supplied

Renal amyloidosis.

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Amyloidosis↗