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Biomedical subjects

R P LYON

Publications and source records attributed to R P LYON.

At least 19 recordsLinked to original sources
PubMed1965

DIFFERENTIAL RENAL FUNCTION STUDY: AN AID IN PREOPERATIVE EVALUATION OF HYPERTENSIVE PATIENTS.

Non-occlusive ureteral catheters were placed bilaterally in the renal pelves of 30 patients known to have hypertension. Samples of urine were collected under conditions of normal hydration, of urea-PAH-saline diuresis and, in some cases, mannitol diuresis. The samples were analyzed for indications of impaired flow of blood to the kidneys. Aortograms were obtained in all cases. This placement of non-occlusive catheters up into the renal pelves was felt to have caused only minimal disturbance of renal function, and was not accompanied by ureteral edema with the concomitant complications caused by occlusive catheters. Under conditions of normal hydration, leakage was insignificant. Of the 20 patients in whom urea-PAH-saline infusion revealed an ischemic pattern, 19 had an ischemic pattern under conditions of normal hydration. Since in the one exception an aortographic examination did not show a surgically reparable renal lesion, it may be inferred that the use of urea-PAH-saline diuresis is not essential in the preoperative evaluation of hypertensive renal disease. Correlation of the results of differential renal function studies and aortographic findings was possible in 19 of the 30 patients. Lack of correlation in the remaining 11 patients emphasized the importance of obtaining both types of study. Aortographic examination combined with differential renal function studies, using small ureteral catheters under conditions of normal hydration, should give the urologist a practical and yet accurate method of determining differential renal blood flow. If desired, further verification could be obtained by administering contrast medium and performing serial measurements of urine density.

Angiography↗
PubMed1963

Nonobstructive oliguria: differential diagnosis.

A review is presented of ten years' experience with the differential diagnosis of oliguria, utilizing the standard tests of renal function with the addition of the phenolsulfonphthalein excretion and urinary chloride measurements. The histories of 60 patients seen in consultation because of 24-hour urinary volume of less than 400 ml were studied in order to clarify the value of these tests. Particular attention was given to the postoperative "dilution state," the oliguria of which tends to mimic that of "acute tubular necrosis."In only 25 per cent of the 60 cases was "acute tubular necrosis" responsible for the oliguria. In the remaining 75 per cent of patients, oliguria was due either to the effects of simple dehydration without tubular damage, or to tubular dysfunction on a physiologic rather than an organic basis. Thus, three out of four patients with oliguria required aggressive and specific fluid-electrolyte therapy, often with the intensive use of potassium. One out of four required the opposite in therapy-controlled dehydration without added potassium and, on occasion, peritoneal or extracorporeal dialysis, in order to allow six to ten days for tubular repair.

Anuria↗
PubMed1951

Extraperitoneal pneumography; a preliminary report.

The presence of a gas in the retroperitoneal tissues makes possible a radiologic visualization of retroperitoneal organs and masses. Retropneumoperitoneum is accomplished by the injection of oxygen at low pressure into the tissues lying between the coccyx and the rectum. The technique of injection is simple and no complications have occurred with the first 30 cases. This method is particularly useful in outlining the kidneys and adrenal glands.

Abdomen↗