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Biomedical subjects

R P Juniper

Publications and source records attributed to R P Juniper.

35 records · Page 2Linked to original sources
PubMed1989

Codeine 20 mg increases pain relief from ibuprofen 400 mg after third molar surgery. A repeat-dosing comparison of ibuprofen and an ibuprofen-codeine combination.

A combination of 20 mg codeine base and ibuprofen 400 mg was compared with ibuprofen 400 mg in a randomised double-blind cross-over study of multiple doses in 25 patients after 2-stage bilateral third molar removal. The combination produced significantly greater pain relief and doubled the hours of minimum pain intensity and maximal relief on the day of surgery. The patients rated the combination significantly better than ibuprofen alone, and the combination was preferred by 16 of the 22 patients expressing a preference. There was no significant increase in side-effect incidence with the combination. The 30% increase in analgesic effect may be of clinical benefit, and this trial design, cross-over with multiple dosing in out-patients, may be a sensitive test for analgesics, potentially more predictive of side-effect problems than single-dose studies.

Adult↗
PubMed1989

Mucosal involvement in systemic and chronic cutaneous lupus erythematosus.

The prevalence and pattern of mucosal involvement in 121 patients with lupus erythematosus (LE) was investigated. Fifty-three patients had systemic LE (SLE) and 68 patients had chronic cutaneous LE (CCLE). Twenty-one per cent (11/53) of patients with SLE and 24% (16/68) of patients with CCLE had signs of mucosal involvement, but the pattern of involvement differed in the two groups. Nasal mucosal lesions were a feature in 2% (I/53) of patients with SLE and 9% (6/68) of patients with CCLE. Hyperkeratotic lichen planus-like plaques on buccal mucosa and the palate occurred in 9% (6/68) of patients with CCLE and 4% (2/53) of patients with SLE. Episcleritis occurred in 9% (5/53) of patients with SLE and not seen in CCLE. Erythematous plaques on the lower eyelids were present in 6% (4/68) of patients with CCLE and these were associated with conjunctival scarring in two patients. Vulval lesions were present in 5% (2/42) of female patients with CCLE. Oral plaques may occur when the disease is relatively quiescent elsewhere. The prevalence of mucosal involvement in lupus is underestimated as the lesions may be asymptomatic.

Adult↗
PubMed1988

Temporomandibular joint arthrography: dynamic study by videorecording.

Temporomandibular joint symptoms are common. Patients not successfully treated by conservative methods require accurate assessment of the internal derangements of the joint. Temporomandibular joint arthrography using only videorecorded intensifier fluorography displays the anatomy and function accurately with a low radiation dose.

Arthrography↗
PubMed1984

Temporomandibular joint dysfunction: a theory based upon electromyographic studies of the lateral pterygoid muscle.

Electromyographic investigations into the function of the two individual heads of the lateral pterygoid muscle in normal persons are compared with patients suffering the pain of temporomandibular joint dysfunction and those with painless clicks. The results indicate that the lower head of the lateral pterygoid muscle, normally active only when depressing, protruding and deviating the mandible, becomes active on closing and clenching in patients suffering pain. Patients with painless clicks behave as normals. These results are discussed and a theory is presented which suggests that temporomandibular joint dysfunction has a simple pathological basis.

Adult↗
PubMed1982

Caffey's disease.

Caffey's disease or infantile cortical hyperostosis is a rare condition affecting infants in the first five months of life. Varying forms of its presentation are illustrated by the four case reports described. The aetiology, pathology, differential diagnosis and management are discussed. It is possible that Caffey's Disease is becoming more frequent, and as the mandible is involved in over 90 per cent of cases, the oral surgeon increasingly may be presented with these cases which can be very difficult to diagnose.

Diagnosis, Differential↗