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Biomedical subjects

R P Bell

Publications and source records attributed to R P Bell.

4 recordsLinked to original sources
PubMed2001

A novel route to the marasmane skeleton via a tandem rearrangement-cyclopropanation reaction. total synthesis of (+)-isovelleral.

A general and efficient route to the marasmane skeleton is described. Total syntheses of two simple marasmanes (35 and 37) in racemic form were achieved using a MgI2-catalyzed rearrangement-cyclopropanation reaction of trimethylsilyl enol ether 31 derived from naphthalenone 30. The reaction proceeds in high yield with complete diastereoselectivity and does not require the use of special cyclopropanation reagents. Application of this novel route to the marasmane framework was extended to the synthesis of naturally occurring (+)-isovelleral (41).

Basidiomycota↗
PubMed1996

Implementing a research-based kangaroo care program in the NICU.

Kangaroo care or skin-to-skin holding of preterm infants requires consistent implementation for best outcomes with infants and families. Successful implementation of a project of this type demands an organized approach. This article describes how a standard of care was developed using research findings and then implemented with a step-by-step approach in the neonatal intensive care unit.

Arizona↗
PubMed1970

Haemodialysis cost reduction by artificial kidney storage: a simple, effective technique for re-use of coil kidneys.

A simple method of storing and re-using coil dialysers was used in over 700 dialysers without serious complications but mantaining the efficiency of the dialyser. The method can reduce the expense of coil and tubing by as much as 70%, while the total cost of home or hospital dialysis can be reduced by as much as 15 to 25% even when the coil is re-used only once. Coils were re-used as many as 14 times, making the potential reduction in cost much larger. This technique deserves further evaluation in both hospital and home dialysis programmes.

Acute Kidney Injury↗