An Rh gene complex producing weak c and E antigens.
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Agglutination Tests↗
Biomedical subjects
R Oyen
Publications and source records attributed to R Oyen.
Glans ischemia after penis revascularization: therapeutic embolization.
A case of hypervascularization of the penis with glans ischemia after venous leakage procedure followed by revascularization of the penis is reported. The venous bypass between the inferior epigastric artery and the dorsal penile artery was misplaced on the deep dorsal vein leading to venous hypertension of the glans. Transcatheter embolization of the venous bypass cured this complication.
Adult↗
Adrenocortical carcinoma with fat inclusion: case report.
Adrenocortical carcinoma is a rare tumor that arises from the adrenal cortex, with an estimated incidence of 0.5% to 2% per 1 million patients yearly. Although some fat content can be expected in hormonally active adrenocortical carcinomas, areas of 100% fat are extremely rare. We present a case of an adrenocortical carcinoma with a small focus of pure fat depicted on magnetic resonance imaging.
Adipose Tissue↗
Inherited mosaicism affecting the ABO blood groups.
Blood samples from two families and three other unrelated people contain a mixture of red blood cells of two different ABO types. Previously described causes of red blood cell mosaicism have been excluded from responsibility. Other blood group systems are not involved. The phenotypes, which have been designated ABO mos, are inherited through a variant allele at the ABO locus and appear to arise from a change in regulation of an ABO gene of some somatic cells.
ABO Blood-Group System↗
A second example of anti-Lu14.
Anti-Lu 14 has been found in the serum of a gravida 2 pregnant woman who had not been given any blood transfusions. Her husband is Lu:14 but otherwise of common Lutheran blood type. Maternal immunization probably occurred during the first pregnancy. The second child did not inherit the father's Lu14 gene and was not affected by the maternal antibody.
Female↗
Naturally occurring anti-Kell stimulated by E. coli enterocolitis in a 20-day-old child.
Anti-A and anti-K have been found in the serum of a 20-day-old child who had not been transfused but who was acutely ill with E. coli enterocolitis. Both antibodies are IgM proteins. The mother's serum does not contain either antibody and the anti-A and anti-K in the infant's serum are not of maternal origin. Both parents and the child are of the Kell phenotype K-k+. Stool cultures made from the child yielded E. coli O 125:B15, an uncommon B-variant pathogenic coliform. Cell-free preparations made from broth cultures of this organism have strong specific inhibitory activity against IgM anti-A and anti-K, and both antigens have been identified on the bacterial cells. At age 3 months the child had made a clinical recovery, stool cultures showed no pathogenic coliforms, and anti-A and anti-K were no longer detectable in her serum. These data indicate that absorption of metabolites with A-like and K-like activity produced by a pathogenic coliform in the intestinal tract were responsible for the appearance of apparent naturally occurring anti-A and anti-K in the child's serum.
ABO Blood-Group System↗
A study of soluble Lewis and P1 substances produced for use in immunohematology.
We have investigated a new source of commercial Lewis and P1 soluble blood group substances produced for use in immunohematology. Our tests show them to be potent, specific, stable and suitable for use in antibody inhibition procedures. They should make a useful contribution to antibody identification studies in hospital blood bank laboratories.
Antibody Specificity↗
Auto anti-Kpb associated with weakened antigenicity in the Kell blood group system: a second example.
An 84-year-old woman with intestinal bleeding had marked reduction of red blood cell antigenicity in the Kell system, and a positive direct antiglobulin test caused by auto-anti-Kpb. KX antigen activity of her cell was increased, an observation which supports the belief that KX marks a precursor structure utilized in the normal Kell biosynthetic pathway. It is postulated that reduced Kell antigenicity was an acquired change that resulted from enzymatic degradation, possibly of bacterial origin.
Adolescent↗
Delayed hemolytic transfusion reaction caused by the second example of anti-K19.
A second example of anti-K19 has been identified in the serum of a black patient immunized by blood transfusions. The antibody was responsible for delayed hemolysis of transfused incompatible red blood cells. The patient's red blood cells are K:--19 but are otherwise of common Kell phenotype. The K19 antigen is closely associated with the Kell blood group although there is, as yet, no pedigree information to confirm that it is produced by the Kell gene. Tests on 10,757 group O blood donors have not revealed any further examples of the K:--19 phenotype.
Anemia, Hemolytic, Autoimmune↗
Anti-Sdx: a "new" auto-agglutinin related to the Sda blood group.
Two examples of a "new" IgM saline-agglutinating auto-antibody are described. The antibodies bind complement, have the ability to cause in vivo hemolysis, and are most active at room temperature at a pH of about 6.5. Despite tests on more than 5,000 people, no nonreactive cell sample has been found. The reactive antigen is not denatured by neuraminidase, papain, or ficin, and is present on i adult red blood cells. The antibodies appear to be slightly inhibited by human saliva and milk, and more convincingly inhibited by urine from Sd(a+) persons. They are not inhibited by urine from Sd(a-) persons, but are strongly inhibited by guinea pig urine. The serologic characteristics indicate a relationship to the Sda blood group and the auto-antibody has been named antiSdx. Sdx antigen is present on red blood cells from some higher primates and is absent from rabbit, rhesus monkey, dog and sheep cells.
ABO Blood-Group System↗
"New" autoantibody specificity in autoimmune hemolytic anemia defined with red cells treated with 2-aminoethylisothiouronium bromide and a dithiothreitol-papain solution.
Specificity of IgG autoantibodies that react with random red cell samples but not with cells treated with 2-aminoethylisothiouronium bromide (AET)-previously was related to the Kell blood group system. We now describe an IgG autoantibody, from a patient who died with autoimmune hemolytic anemia, that reacted with random red cell samples, Ko cells, and with cells treated with a dithiothreitol-papain solution, but did not react with AET-treated cells or with Rhnull cells. Serological reactivity of the autoantibody is unlike that of IgG autoantibodies that do not react only with Rhnull cells. It appears that the reactive antigen is not part of the Kell or Rh systems, but is probably modified by the membrane anomaly present in Rhnull red cells.
Aged↗
Comparison of human and chimpanzee Kell blood group systems.
Kell antigens on chimpanzee (Pan troglodytes) red cells were determined using specific human alloimmune and murine monoclonal antibodies. After avoidance of interspecies reactions, chimpanzee red cells were found to react with most Kell system antibodies. The chimpanzees had phenotypes similar to those of humans. The main difference was that all of 27 chimpanzee red cell samples tested were of the K:6, -7, phenotype, while in humans most are K:-6, 7. The most common chimpanzee Kell blood group phenotype was K:-1,2,-3,4,5,6,-7,11,12,13,14, 15,18,19,22. Murine monoclonal anti-K2 and -K14 immunoprecipitated a 97-kD protein from chimpanzee red cells and a 93-kD protein from human red cells. Enzymatic deglycosylation yielded proteins of about 79 kD for humans and 77 kD for chimpanzees. Both human and chimpanzee Kell proteins reacted equally well on Western blots with polyclonal rabbit antibody to human Kell protein, which indicated close homology.
Adult↗
Correlation of sonographic patterns in liver metastases with histology and microangiography.
Thirty-three livers with microscopic metastatic involvement were studied at autopsy by high resolution real time ultrasound at 7.5 and 10 MHz. Eighteen lesions with different sonographic appearances were selected for further microangiographic and histologic analysis. Tumor vascularity was assessed on microangiography. The anatomic pathologic study included both the evaluation of the microscopic and histologic appearances.
Adenocarcinoma↗
Computed tomography of infected epiglottic cyst.
A case of infected ductal epiglottic cyst demonstrated by CT is reported. Computed tomography appears to be an excellent, noninvasive examination that provides the exact diagnosis and clear extent of the disease.
Cysts↗
Stenosing hemorrhagic ureteritis in a child with Henoch-Schönlein purpura: CT appearance.
Henoch-Schönlein purpura is rarely considered in the differential diagnosis of ureteral obstruction in children. Renal ultrasound and intravenous urography may reveal hydroureteronephrosis but usually fail to yield a specific diagnosis. In this child CT differentiated between an intrinsic ureteral stenosis (hemorrhagic ureteritis) and an extrinsic ureteral stenosis (retroperitoneal fibrosis), two rare complications of Henoch-Schönlein purpura. The CT findings of hemorrhagic ureteritis are described.
Child↗
Renal pseudotumor due to a retained perirenal sponge: CT features.
A case of a surgically retained, encapsulated sponge presenting as an unusual cause of renal pseudotumor is described in a man who had a partial nephrectomy for renal cell carcinoma 1 year before. The nonspecific sonographic appearance of a hyperechoic renal mass and the atypical CT features of a thick-walled indeterminate mass suggested a hematoma, a hemorrhagic cyst, or a hemorrhagic neoplasm. A retained surgical sponge within a thick fibrotic capsule adhesive to the renal capsule was found at surgery.
Diagnosis, Differential↗
Use of Escherichia coli O 86 :B7 in the adsorption of anti-A and anti-B from blood typing sera.
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Antibody Specificity↗
Kidd blood-group antigens of leukocytes and platelets.
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Absorption↗