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R Oyen

Publications and source records attributed to R Oyen.

At least 55 records · Page 3Linked to original sources
PubMed1997

Is intravenous urography still used in patients with prostatism?

The value of intravenous urography in patients with prostatism was retrospectively evaluated. One thousand four hundred ninety five intravenous urograms of male patients referred by the department of urology were reviewed. Based on the clinical information, only patients with complaints of prostatism as a single symptom were selected. Patients with associated symptoms (i.e. hematuria, urinary infection) were excluded. Forty seven patients could be included based on these criteria. In 29 of 47 cases (61.7%) no abnormalities were found. Abnormalities found in 18 cases included dilatation of the excretory system, urinary calculi, congenital anomaly, acquired small kidney, renal cysts and retroperitoneal fibrosis. In 5 cases (10.1%) the intravenous urography necessitated further treatment and/or follow up. In 3.1% prostatism was the indication for the examination. The number of relevant abnormalities at intravenous urography performed for prostatism is low and this is in accordance with results reported in literature. These results provide further evidence for the continuously changing indications for intravenous urography.

Aged↗
PubMed1996

A new low-incidence antigen in the Kell blood group system: VLAN (KEL25).

A multilaboratory investigation has identified a new low-incidence antigen "VLAN' on the red cells of a blood donor. The VLAN antigen is destroyed by 2-aminoethylisothiouronium bromide treatment of the donor's red cells suggesting an association with the Kell system. Monoclonal antibody-specific immobilization of erythrocyte antigen analysis with anti-VLAN and with several mouse monoclonal antibodies directed at epitopes on the Kell glycoprotein gave positive results, indicating that the VLAN antigen is located on the Kell glycoprotein. The VLAN red blood cells have the common Kell phenotype: KEL:-1,2,-3,4,5,-6,7,-10,11,12,13,14,-17,18,19,-21,22,-23,-24. Additional serologic data indicate that the VLAN antigen is not part of any other ISBT blood group system, collection or series. A family study showed that the VLAN antigen is inherited since the red cells of two sisters and one niece of the propositus are also VLAN+. The ISBT Working Party on Terminology for Red Cell Surface Antigens has assigned VLAN to the Kell blood group system as KEL25 (number for computer listings 006025).

Antigens↗
PubMed1996

The case against fine-needle aspiration cytology for small solid kidney tumors.

Conservative renal cell cancer surgery in elective conditions can be applied if the tumor is solitary and well delineated on the CT scan and easily resectable within a rim of healthy parenchyma. A number of solid tumors will prove not to be malignant on definite pathological examination. The radiological preoperative differential diagnosis of a small renal mass is not always obvious. The efficacy of fine-needle aspiration cytology in recognizing the pathology of the tumor before surgery is limited and major complications have been reported. Moreover, it can render a conservative surgical procedure less safe. Thus fineneedle aspiration cytology is not recommended if conservative surgery is planned, unless renal involvement by metastasis or lymphoma is suspected.

Biopsy, Needle↗
PubMed1995

Extramedullary hematopoiesis encasing the pelvicalyceal system: CT findings.

A rare case of symmetric renal extramedullary hematopoiesis is hypothesized in a patient with long-standing Vaquez' disease and myelofibrosis. At CT, soft tissue densities were found in the renal hilar area encasing the pelvicalyceal system. Although there is nothing specific about the CT findings, the diagnosis can be suggested in the proper clinical setting. The association with generalized osteosclerosis is another diagnostic clue.

Diagnosis, Differential↗
PubMed1995

Selective protection against IgG binding to red cells treated with phthalocyanines and red light for virus inactivation.

BACKGROUND: Irradiation with red light of red cells (RBCs) containing the photodynamically active phthalocyanine (Pc) dyes is being studied for inactivation of lipid-enveloped viruses. One of the outstanding problems with this treatment is the binding of IgG to RBCs. The effects of oxygen and type I or type II quenchers on this IgG uptake were evaluated. STUDY DESIGN AND METHODS: The Pc compounds used were aluminum phthalocyanine tetrasulfonate (AIPcS4), HOSiPcOSi(CH3)2(CH2)3N(CH3)2 (Pc 4); HOSiPcOSi(CH3)2(CH2)3N+(CH3)3I- (Pc 5); and SiPcOSi[(CH3)2(CH2)3N+(CH3)3](2)2I- (Pc 6). RBCs were analyzed by flow cytometry for the presence of IgG. RESULTS: Irradiation with red light for 30 minutes of RBCs containing either 2 microM Pc 4, 2 microM Pc 5, 2 microM Pc 6, or 6.5 microM AIPcS4 resulted in an uptake of IgG. These conditions completely inactivated the lipid-enveloped vesicular stomatitis virus (VSV) (> 5 log10 kill). IgG uptake was reduced when oxygen was depleted. The addition of reduced glutathione (GSH) or mercaptoethanol prevented the binding of IgG with RBCs treated with AIPcS4, Pc 4, Pc 5, and Pc 6. Specific binding of IgG2 but not of C3d was observed upon irradiation of RBCs with Pc 5 and Pc 6 in the absence of GSH. No gross changes were observed in RBC antigen strength after irradiation with the dyes in the presence of GSH. Inactivation of VSV by Pc plus light was not affected by GSH. CONCLUSION: Sulfhydryl compounds are useful in preventing IgG binding to RBCs following Pc photosensitization. Since virus inactivation proceeds at the same rate in the presence and the absence of sulfhydryl compounds, their addition to treated RBCs should allow crossmatching for transfusion after treatment. The binding of IgG depends to a large extent on the generation of reactive oxygen species.

Antiviral Agents↗
PubMed1995

Neoadjuvant hormonal therapy before radical prostatectomy decreases the number of positive surgical margins in stage T2 prostate cancer: interim results of a prospective randomized trial. The Belgian Uro-Oncological Study Group.

PURPOSE: We investigated the effect of neoadjuvant treatment before radical prostatectomy for clinically localized prostate cancer. MATERIALS AND METHODS: A total of 130 patients with stages T2b and T3 prostate cancer was randomized in a multicenter study: 62 underwent immediate radical prostatectomy and 65 received 560 mg. estramustine phosphate daily for 6 weeks preoperatively. RESULTS: For clinical stage T2b tumors the neoadjuvant treatment resulted in a significant decrease in positive surgical margins compared to the nonpretreated group. This difference was not found for clinical stage T3 tumors. The impact on progression and survival still must be analyzed. CONCLUSIONS: Neoadjuvant treatment can be beneficial for clinical stage T2 prostate cancer. Optimal treatment for stage T3 tumors remains controversial.

Aged↗
PubMed1995

A novel common Kell antigen, TOU, and its spatial relationship to other Kell antigens.

A 47-year-old native American (TOU) was admitted to hospital for hip surgery. His serum agglutinated all red blood cells (RBCs) tested except Ko and DTT-treated RBCs and was weakly reactive with RBCs known to have a weak expression of Kell antigens, namely Kmod, McLeod, Kp(a+b-) (KEL:3,-4) and K:-13 (KEL:-13) phenotypes. RBCs from three siblings, a son and a daughter were incompatible with TOU's antibody. TOU's RBCs had the common Kell phenotype: K-k+Kp(a-b+c-)Ku+Js(a-b+)Ul(a-)K:11,-17K:14,-24K:12,13,18,19, 22,-23(KEL:-1,2,-3,4,5,-6,7,-10,11,12,13,14,-17,18,19,-21,22,-23,-24). Since TOU's RBCs were not agglutinated by an unidentified Kell-related antibody (IAN), tests were performed to show that TOU and IAN were mutually compatible. IAN is a Latino female hospitalised for a hysterectomy. The TOU antigen was shown to be located on the Kell glycoprotein by a monoclonal antibody immobilisation of erythrocyte antigen (MAIEA) assay. The unique pattern of reactivity obtained with TOU and IAN antibodies using this assay indicated the TOU epitope to be in an area remote from other Kell antigens, namely K, k, Kpa, Kpb, Kpc, Ku, Jsa, Jsb, U1a, K11, K12, K13, K14, Wka, K18, K19, K22 and K24 (KEL1, KEL2, KEL3, KEL4, KEL5, KEL6, KEL7, KEL11, KEL12, KEL13, KEL14, KEL17, KEL18, KEL4, KEL5, KEL6, KEL7, KEL11, KEL12, KEL13, KEL14, KEL17, KEL18, KEL19, KEL21, KEL22 and KEL24) but close to the low-incidence antigen K23 (KEL23).(ABSTRACT TRUNCATED AT 250 WORDS)

Female↗
PubMed1995

K12 is located on the Kell blood group protein in proximity to K/k and Jsa/Jsb.

K12 is a high-prevalence antigen, with no known antithetical partner, that is associated with the Kell blood group system. We report studies on the 5th propositus (MS) with the K:-12 phenotype and the second case to show that the K12 is inherited. The anti-K12 in his serum did not destroy antigen-positive incompatible red cells transfused on at least 3 occasions over 6 years. Red cell membranes from MS possessed the Kell protein that was indistinguishable from control membranes. K12 antigen was shown by immunoprecipitation to be on a protein with an apparent molecular mass of 93,000 and by monoclonal antibody immobilization of erythrocyte antigens (MAIEA) assay to be on the Kell protein in proximity to K/k and Jsa/Jsb antigens. These data remove the K:-12 phenotype from its current Kell-related (or para Kell) status and elevates the K12 antigen to a bona fide member of the Kell blood group system.

Antibodies, Monoclonal↗
PubMed1995

Juxtaglomerular cell tumor: importance of clinical suspicion.

This case report of a reninoma or juxtaglomerular cell tumor illustrates that careful preoperative radiological investigation and preoperative frozen-section examination does not always lead to a correct diagnosis. The preoperative diagnosis of juxtaglomerular tumors should therefore primarily depend upon clinical suspicion, eventually followed by directed renal vein renin ratio blood sampling. The importance of early preoperative diagnosis and treatment is stressed.

Adenocarcinoma↗
PubMed1995

Case report: pseudotumoral pelvic retroperitoneal fibrosis associated with orbital fibrosis.

We report the case of a man with bilateral orbital fibrous pseudotumours and a large pelvic mass which was initially thought to be malignant. Sonographically guided transrectal core biopsies showed it to be a fibrotic retroperitoneal pseudotumour. The mass decreased after steroid therapy. The computed tomography and magnetic resonance imaging features of this unusual form of pelvic fibrosis as well as the association with heterotopic fibrosis are discussed.

Fibrosis↗
PubMed1995

Retroperitoneal schwannoma.

A case of an incidentally found retroperitoneal schwannoma is reported. A schwannoma is a rare, benign tumor affecting the soft tissues and the viscera. In the presented case, the US and CT images suggested the nature of this benign tumor. Angiography confirmed the mass effect on the portal vein and subsequently the potential risk of portal thrombosis. The diagnosis was confirmed at surgery.

Angiography↗
PubMed1995

[Spiral CT in parenchymatous disorders of the kidney].

Spiral-CT enables accurate diagnosis of renal parenchymal diseases and tumors, and when necessary, staging. Important prerequisites are optimal timing after injection of contrast medium and problem-tailored reformatting. In the optimal setting, this allows to reduce the examination time, the radiation dose, and the dose of contrast medium. Moreover, many other so-called complementary examinations as MRI, angiography, cavography, and diagnostic puncture can be avoided.

Adenocarcinoma↗
PubMed1995

The history of uroradiology.

In the first period (1896-1910), investigation was made through plain abdominal film with description and differential diagnosis of the different calcifications in the right hypochondrium. Second period (1911-1924): indirect signs of liver and gallbladder pathology were described. Via pneumoperitoneum and gastro-intestinal opacification the pathology in the right hypochondrium was delineated and interpreted. Third period (1924 until now): due to the development of contrast agents for the gallbladder and biliary tree, these organs could be directly visualized either by intravenous injection, or by peroral administration; sometimes direct injection of contrast in the bile ducts was used.

History, 19th Century↗