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Biomedical subjects

R Orda

Publications and source records attributed to R Orda.

At least 73 records · Page 4Linked to original sources
PubMed1985

Intestinal neurofibromatosis. Multiple complications in a single case.

The use of radionuclide gastrointestinal scanning with 99mTc sulfur colloid, supplementing angiography, is described in the diagnosis of the source of bleeding in a 60-year-old woman with neurofibromatosis. These two procedures succeeded in locating the origin of bleeding from neurofibroma in the jejunum, which was corrected by surgery. To our knowledge, this case report is the first description of a patient with neurofibromatosis, with all the reported gastrointestinal symptoms: intermittent abdominal pains, palpable abdominal mass, gastrointestinal bleeding and small bowel obstruction.

Digestive System↗
PubMed1984

Lipase turbidimetric assay and acute pancreatitis.

The simplified turbidimetric assay for lipase activity was used for the differential diagnosis of acute pancreatitis. Serum lipase levels were found to be increased in a group of 17 patients in whom acute pancreatitis was clinically suspected and confirmed by a high ACCR and decreased uptake of the radionuclide in the pancreas scan. The lipase levels were within normal limits in a control group of 14 patients suffering from diseases other than acute pancreatitis. The turbidimetric test was helpful for rapid quantitative determination of serum lipase and thus for the early and accurate diagnosis of acute pancreatitis.

Acute Disease↗
PubMed1982

Hemisplenectomy using a hand-held CO2 laser. An experimental study.

Hemisplenectomy was performed in mongrel dogs using a hand held CO2 laser. Cutting and hemostasis were performed by a laser beam with a high concentration power--about 6kW/mm2--at the focal spot, and residual bleeding was controlled by using a defocused beam. The cutting action was improved by temporary closing of the arterial vessels and by injecting adrenaline into the splenic artery to produce a relatively dry surface. The surgical procedure was free of mortality or morbidity. Histological studies revealed a brand of fibrous tissue at the cut surface, without apparent abnormalities in the splenic parenchyma beneath the section. Activity of the residual half spleen was shown by postoperative technetium scan and by the fact that Howell-Jolly bodies appeared in peripheral blood only after resection of the remaining half spleen.

Animals↗
PubMed1981

Postsplenectomy splenic activity.

Evidence of recurring activity of splenic tissue was investigated in patients who had undergone splenectomies. Methods included technetium 99m sulfur colloid scan, serum tuftsin assay, serum immunoglobulin concentration, blood cell counts, and search for Howell-Jolly bodies. Positive scans were observed together with normal levels of tuftsin in 54% of the patients. In 46% of the patients, no splenic activity was detected by scanning and low levels of tuftsin were noticed. The difference in tuftsin levels between the two groups was statistically significant. Howell-Jolly bodies and decreased serum levels of IgM featured all patients. The possible application of combined splenic scan and tuftsin assessment for screening recurring splenic activity in the postsplenectomy population at great risk is suggested.

Adolescent↗
PubMed1981

Retrograde urography with a new antiseptic contrast contrast material. An experimental study.

A new antiseptic contrast material, composed of sodium diatrizoate-meglumine diatrizoate and PVP-iodine solution, was prepared and tested for retrograde cystography. It was tested in vitro and in dogs, showed satisfactory radiological features and rapid wide bactericidal action without detectable side effects. Septic complications following radiological demonstration of the urinary tract may be reduced.

Animals↗
PubMed1980

Experimental acute pancreatitis. Inducement by taurocholate sodium-trypsin injection into a temporarily closed duodenal loop in the rat.

Experimental pancreatitis induced by permanently closed duodenal loop results in death of the experimental animal. Acute pancreatitis can be induced in the rat by injection of taurocholate sodium-trypsin solution intraluminally into a temporarily occluded duodenal loop. Mortality in this model was 45% within one week after injection. Mean serum amylase level was greatly increased above that in control rats that underwent temporary duodenal ligation without intraduodenal injection of fluid. The presence of pancreatitis was confirmed by histological examination. The advantage of the temporarily occluded pancreatitis model is that the animal can survive if the stimulus is not excessively severe.

Acute Disease↗
PubMed1980

Partial distal pancreatectomy with a hand-held CO2 laser. An experimental study.

Partial distal pancreatectomy was performed in dogs with CO2 laser. Results were compared with those obtained with use of diathermy and scalpel. Postoperative hyperamylasemia appeared in all the animals. The highest peaks in the laser and scalpel groups were found on the fifth postoperative day, after which they gradually returned to normal; the highest levels appeared in the diathermy group on the 21st day, and returned to normal only after 56 days. Pancreatography showed a sealed duct in the laser and diathermy groups although no duct ligation was performed. Histological study of the laser group disclosed initial thermal injury at the cut section with no damage to the nearby parenchyma, followed later by a smooth, thin scar. In the diathermy and scalpel groups, the injured zone became enlarged later by active parenchymal and interlobular inflammation in the underlying tissue.

Amylases↗
PubMed1978

Self-established porto-caval and porto-pulmonary shunts in mechanically induced portal hypertension. An experimental study.

Portal hypertension was mechanically induced in rats by partial constriction of the portal vein. Angiography revealed the spontaneous development of porto-systemic and porto-pulmonary shunts in all hypertensive animals. A coincident decompression of the portal system was recorded. Release of the portal vein constriction led to disappearance of the collaterals in most of the experimental animals.

Animals↗