The oxidation of the fatty acids in vitro, with especial reference to the oxidation of beta-hydroxybutyric and acetoacetic acids.
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Journal Article↗
Biomedical subjects
R O Jones
Publications and source records attributed to R O Jones.
The oxidation of phenyl derivatives of fatty acids with hydrogen peroxide in the presence of copper.
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Journal Article↗
Pedal consequences of rhabdomyolysis: a case report.
The authors present an unusual case that has been seldom reported in the literature. The clinical rhabdomyolysis syndrome, resulting from muscle disintegration, can be the result of numerous etiologic events and have serious sequelae. The pedal manifestations result from muscular and neurologic insult. The patient in this reported case survived rhabdomyolysis despite renal and hepatic failure requiring diuresis and hemodialysis. The only permanent long-term sequelae the patient suffered was flexible hammertoe deformities and parasthesias of all lesser digits of both feet. The follow-up is over 8 years.
Adult↗
Comparisons of tracheostomy incisions in a pediatric model.
Tracheostomy in children causes approximately twice the mortality and morbidity as in the adult. The occurrence of complications correlates closely with the severity of the preoperative tracheal disease, the length of time the tracheostomy is needed, and the age of the patient. Morbidity documented in the postoperative period includes tracheal stenosis and collapsible anterior tracheal wall. The increased incidence of these problems in the pediatric patient may be related to the less rigid nature of the younger cartilage or to partial arrest of the normal tracheal growth rate, and may be aggravated by the style of tracheal incision used. Our study utilized weanling male ferrets in an effort to evaluate the possibly different response of growing, less resilient cartilage to different types of tracheal incision. Animals were randomized into three groups based on the type of incision used: inferiorly based trapdoor, vertical slit, or horizontal H. Endoscopic, radiographic, and airflow studies, as well as cross-sectional areas, were compared on all animals surviving tracheal cannulation for eight days and subsequent decannulation for seven days. Recommendations for pediatric tracheal incision are made on the basis of these studies.
Animals↗
Austin bunionectomy: postoperative MRI evaluation for avascular necrosis.
The authors used magnetic resonance imaging (MRI) to evaluate the formation rate of avascular necrosis following performance of 20 modified Austin bunionectomies. Five modified McBride bunionectomies without first metatarsal osteotomy were also performed as an MRI control. Results showed an avascular necrosis formation rate of 50%. The majority of the avascular necrosis areas were found dorsally within the cancellous bone substance of the first metatarsal head. These lesions, in all cases, did not cause any patient disability or result in any decline in the degree of patient satisfaction. The MRI positive avascular necrosis evaluations do suggest potential problem areas with the surgical technique that may be eliminated through further modification of the classic Austin bunionectomy procedure.
Adult↗
Intra-operative contamination of bone and cartilage during an Austin bunionectomy.
During an Austin bunionectomy the potential exists for the head of the metatarsal to leave the sterile field and become contaminated. The authors present a case in which this occurred, with a 20-month follow-up. Possible options for decontamination are reviewed.
Adult↗
Comparison of oblique closing base wedge osteotomies of the first metatarsal: stripping versus nonstripping of the periosteum.
The authors present a study comparing two methods of performing the oblique closing base wedge osteotomy of the first metatarsal for correction of hallux abducto valgus deformity. In one group, the periosteum was stripped from the metatarsal prior to performing the osteotomy, and in the other group, the osteotomy was performed through the periosteum. Sixty-five osteotomies are included in the study. This article discusses the closing base wedge osteotomy, fracture healing and the role of the periosteum, the blood supply to the first metatarsal, and the effects of periosteal stripping. Also included is a presentation of the surgical technique used, a statistical review of the procedures performed, a critical discussion summarizing the results, and a discussion of the postoperative complications encountered.
Female↗
Retrospective statistical analysis of factors influencing the formation of long-term complications following hallux abducto valgus surgery.
A retrospective analysis was performed to determine the long-term results of hallux abducto valgus surgery done under the auspices of the Texas Health Science Center at San Antonio and its teaching hospitals. Two hundred eighty-five patients with a postoperative follow-up ranging from 3 to 10 years were studied. Attempts were made to study many of the patient demographic factors and perioperative procedures that acted to affect the development of a long-term complication. It was found that type of procedure, past medical history, age, medical control, and location of the surgical suite were all important variables to consider in this regard.
Adolescent↗
Avascular necrosis of the first metatarsal head following Austin osteotomy: a follow-up study.
A prospective study is described of 12 consecutive patients with hallux abducto valgus deformity in whom an Austin osteotomy without lateral release was performed. All patients had similar postoperative care and magnetic resonance images (MRI) studies of their first metatarsals. The MRI was performed in T1- and T2-weighted images with algorithms programmed to image changes in the bone consistent with avascular necrosis of the first metatarsal head. One of the 12 patients following Austin osteotomy without lateral release had changes on MRI consistent with avascular necrosis of the first metatarsal head. These results were then compared with the prior study of 20 patients that had the Austin osteotomy with lateral release using the Fisher's exact test for small populations, and a value of 0.023 was found (0.05 > 95% confidence level). The Austin osteotomy with lateral release significantly increases the risk of developing avascular necrosis of the first metatarsal head and should only be performed in instances where the soft tissue contracture is largely contributing to the hallux abducto valgus deformity.
Follow-Up Studies↗