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Biomedical subjects

R Nessi

Publications and source records attributed to R Nessi.

At least 55 records · Page 3Linked to original sources

[Xeroradiography in radiotherapy of tumors of the bone and soft parts: value in the beginning of therapy in long-term follow-up studies].

Xeroradiography was performed on 38 cases of bone or soft tissue tumors submitted to radiotherapy. The examination was done before, during and after the radiological treatment and at longer intervals after the completion of its course. The indications and the drawbacks of xeroradiography for the follow-up of irradiated cases and for the search of recurrences are discussed, taking also into account the other radiological techniques used in this field. Xeroradiography is held to be very useful in planning the treatment of malignant bone tumors with extraosseous spread, since it allows to establish the real limits of the tumor to be irradiated. Moreover, xeroradiography is helpful to recognize the radiotherapeutic sequelae on superficial soft tissues, as oedema, fibrosis and necrosis of the subcutaneous fat and skin.

Bone Neoplasms↗

[The value of mammography in 1203 breast cancers (author's transl)].

The value of clinical mammography is reviewed on 1203 consecutive cases of histologically proven breast malignancies examined from 1971 to 1978 at the Istituto Nazionale Tumori, Milan, and at the Radiological Department, University of Milan. The diagnostic effectiveness of mammography in this case-list corresponds to approximately 80%: the influences of the histotype and of the tumor's size on these results are reviewed and discussed. The main radiographic signs of malignancy are presented and their importance in reaching a correct diagnosis is outlined. The advantages and drawbacks of mammography are discussed and, amongst these latter, emphasis is given to structurally dense breasts as an intrinsic factor limiting the effectiveness of mammography.

Adolescent↗

[Radiological diagnosis in 229 cases of breast fibroadenoma].

From 1976 to 1977, 705 patients with a fibroadenoma of the breast, histologically proven by biopsy, were observed at the Istituto Nazionale Tumori of Milan. In 229 cases, the clinical examination was followed by mammography or xeromammography; in 65/229 patients telethermography was also carried out. The aspects of fibroadenoma at x-ray examinations are described together with the difficulties to reach an exact diagnosis: the cases in which a false positive diagnosis of cancer was done are emphasized.

Adenofibroma↗

[Xeroradiographic diagnosis of lipomas].

The use of xeroradiography for the study of lipomas (limbs, thoracic wall, pelvic and shoulder girdles) was evaluated on 36 consecutive patients; in 16 cases (44%), histological diagnosis on the surgical specimen was also available. Xeroradiography was more effective than standard x-ray films in 13 cases of 14 submitted to both examination (93%). It allowed to evaluate in detail the size, site and relationships of lipomas as well as to establish their nature. The advantages and drawbacks of xeroradiography in each situation and for the different histological groups of lipomas are discussed. This technique is proposed as a simple and quick procedure for the preoperative diagnosis of lipomas.

Arm↗

Lipoblastic tumours of somatic soft tissues: a xerographic evaluation of 67 cases.

The role of xeroradiography for the diagnosis and the clinical evaluation of lipoblastic tumours of somatic soft tissues was investigated in 67 patients. Xeroradiography improved the visibility of soft tissues over film radiography in 20 out of the 23 cases in which both examinations were performed. The xeroradiographic characters of a lipoblastic tumour depend on its nature, thus irregular and infiltrative masses are usually liposarcomas, while regular and rounded nodes are usually pure or mixed lipomas. Moreover, pure lipomas are always radiolucent and liposarcomas are always radiopaque. Xeroradiography is regarded as a promising first technique in the diagnosis of lipoblastic tumours, before more complex investigations, like computed tomography (CT) scanning or arteriography, are undertaken.

Evaluation Studies as Topic↗

Late metastasis fro neuroblastoma mimicking Ewing's sarcoma.

The case of an unusual late metastasis of neuroblastoma to the calcaneum, appearing as a sole recurrence 9 years after surgery, is reported. The radiographic features of the osseous lesion were very suggestive of primary bone malignancy, Ewing's sarcoma as the first option, with extraosseous spread to the soft tissues.

Bone Neoplasms↗

Pulmonary and mediastinal xerotomography: a critical appraisal.

Xerotomography was performed on 148 patients with proven or suspected tumors of the lung or mediastinum. Retrospectively they were compared to film tomography in 108 cases. In 64 patients, the results of histological examination were also available. Xerotomography proved diagnostically more effective than film tomography in 52 cases (48%), less effective in 6 cases (6%) and about equivalent in the remaining 50 cases (46%). Xerotomography appeared to be more effective in visualization of small peripheral nodes of moderate opacity. Xerotomography has to be a selected second-line technique for special cases, in particular for the study of coin lesions, for the search for cavitations and calcifications and for the study of pulmonary vessels.

Humans↗

Xeroradiography of bone and soft tissue tumors.

Xeroradiography was used for the study of 233 cases of bone and soft tissue tumors, both benign and malignant, 177 of which were histologically proven. In 150 cases, comparative x-ray films were also available. In bone tumors, xeroradiography was more effective than film radiography in 33 cases (44%), less effective in 16 cases (22%) and the 2 techniques were substantially equivalent in 25 cases (34%). In soft tissue tumors, xeroradiography was more effective than film radiography in 59 cases (78%), less effective in 2 cases (3%) and equivalent in 15 cases (19%). Xeroradiography is held to be a useful second-line technique in selected bone tumors, in particular for the study of trabecular structure, periosteal calcifications and cortical bone. In the field of soft tissue tumors, xeroradiography can be a promising first-choice examination in the presence of a mass or when a recurrence is suspected. The advantages and drawbacks of this technique in both types of tumors are reviewed and discussed.

Bone Neoplasms↗

Clinical use of rifampicin in combination for non-mycobacterial infections: a survey of published evidence.

The literature on the clinical use of rifampicin in combination for the treatment of non-mycobacterial diseases is reviewed. From the published evidence, the most promising associations are, for staphylococcal infections, gentamicin, erythromycin, kanamycin and fusidic acid. In the field of Gram-negative infections, Psuedomonas-induced sepsis in particular, data are not so impressive but promising results have been obtained with the associated use of rifampicin and gentamicin or colistin. Some systemic fungal diseases may be successfully treated with rifampicin in combination with amphotericin-B. Although only few reports are available on this subject, the importance of such an application is stressed in view of the severity of these diseases and of the lack of appropriate treatments.

Amphotericin B↗

[Xeroradiographic diagnosis of bone tumours (author's transl)].

The value and drawbacks of xeroradiography were evaluated on 130 patients with benign and malignant bone tumors, 93 of which (72%) were submitted to histological control. Xeroradiography was compared to standard film radiography in 115 cases (88%). In 57 cases (50%), xeroradiography appeared to be more effective than film radiography; it was less effective in 17 cases (15%) and the two techniques were substantially equivalent in the remaining 41 (35%). The best results of xeroradiography were found in malignant tumors, in particular in the presence of an extraosseous spread of the lesion, and it was highly effective in Ewing's sarcoma. According to the sites examined, xeroradiography was more effective in the skeleton of the extremities, while the examination of the trunk and the head were frequently unsatisfactory due to the low sensitivity of this technique. Xeroradiography is held to be an useful second-line examination, to be performed in neoplastic lesions of the limb bones, for the search of small trabecular irregularities, of periosteal reactions or of extraosseous spread of the tumor.

Adolescent↗

Soft tissue xeroradiography.

Xeroradiography of soft tissue lesions, both malignant and benign, has been performed on 121 patients, 79 of whom having also undergone conventional film radiography. In 72 cases (59%), the diagnosis was proved by surgery and histological examination. Xeroradiography was found to be more effective in representing soft tissues than film radiography in 63 cases (80%) and equally effective in 16 cases (20%). Film radiography has never given a better representation of soft structures. The main xeroradiographic aspects of soft tissue lesions are reviewed. A diagnosis of the nature of the lesions on the basis of the extraosseous xeroradiographic picture is deemed possible only for lipomas. In the remaining cases, xeroradiography may offer useful information as regards size, shape and anatomic relationships of lesions but does not allow univocal diagnosis of their nature. Advantages and drawbacks of this technique are discussed, with emphasis on radiation dosage. It is assumed that xeroradiography may prove to be a helpful second-line examination in patients with soft tissue masses or swelling. It may also offer a simple method for follow-up in tumors of soft tissues having undergone conservative treatment.

Abdominal Muscles↗

[Xerography in the study of soft tissues (author's transl)].

Xerography has been used for studying soft tissue lesions in 39 patients, a standard film being taken of 25 for comparison purposes. Xerography proved more effective than film radiography in outlining soft tissue masses. Advantages and drawbacks are discussed, stress being laid on radiation dosage.

Abscess↗