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Biomedical subjects

R Narayan

Publications and source records attributed to R Narayan.

14 recordsLinked to original sources

Sheehan's syndrome following eclampsia: a case report.

A case of Sheehan's syndrome following eclampsia is presented. The clinical features were not recognised early probably because the condition was not suspected, being a rare sequel of eclampsia. Non availability of specialist care may have been partly responsible and is highlighted. Increased awareness of all possible aetiological factors in this condition is necessary for clinicians.

Adult

Endomyocardial biopsy in infants and children with cardiomyopathy.

We reviewed our experience of endomyocardial biopsy performed on 21 symptomatic infants and children with cardiomyopathy. Clinical congestive cardiomyopathy was noted in 18 patients, 2 had hypertrophic cardiomyopathy, and 1 a restrictive cardiomyopathy. The biopsy findings led to a diagnosis of hemochromatosis in one patient, Adriamycin cardiomyopathy in another, and lymphocytic myocarditis in a third. Five patients had features of endocardial fibroelastosis, one endomyocardial fibrosis, and a further one, a mitochrondrial abnormality. In 11 patients normal or nonspecific features were seen. There were 2 myocardial perforations, both patients being successfully resuscitated. Endomyocardial biopsy, although occasionally hazardous, may sometimes provide valuable information which may lead to a diagnosis, facilitate treatment, and be of prognostic value. Despite the low positive yield, it may still be indicated in selected patients, in view of the seriousness and often poor prognosis of this disorder: 5 of our study group subsequently died.

Adolescent

Is ectopic pregnancy too often diagnosed too late?

An increasing incidence of ectopic pregnancy resulted in 177 women being treated at National Womens's Hospital in 1979 and 1980. However, only 65% of women were diagnosed and treated within 24 hours of admission. The affected tube was conserved in only 24% of women. Blood transfusion was required in 52 patients (29%) and in one quarter of these cases, the diagnosis was not made within 24 hours of admission. Four of 20 patients who were discharged and readmitted before the diagnosis was made required blood transfusion, and one of these women was shocked. Women who present with pelvic pain and vaginal bleeding after less than 9 weeks amenorrhea and have pelvic tenderness and abdominal rebound tenderness, must be suspected of having an ectopic pregnancy. Early laparoscopy may then reduce the need for both transfusion and radical tubal surgery.

Adult

Early insults to the injured brain.

Of 100 consecutive patients with severe head injury who arrived at a major trauma center, half of whom came direct from the accident site and half from another hospital, potentially serious systemic insults to the brain were present in 44 cases. Arterial hypotension (13 cases), anemia (12 cases), and hypercarbia (4 cases) were almost exclusively associated with multiple injuries, which were present in 57 patients and were caused usually by vehicular accidents. Hypoxia was seen in 30 patients, including several with brain injury alone. These systemic insults to the already injured brain were associated with an increase in mortality and morbidity. We believe that direct transfer to a trauma center that has full-time neurosurgical facilities for victims of automobile accidents and patients who have been rendered unconscious by a fall or blow on the head will increase survival. Care for the patient with head injuries should start at the roadside.

Accidents, Traffic