Atrial natriuretic factor.
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Biomedical subjects
Publications and source records attributed to R Narang.
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Male albino rats were used to study the osteogenic potential of demineralized allogeneic bone matrix (DABM) grafts, in different stages of demineralization, placed in the anterior abdominal wall. The clinical evaluation, radiologic examination, calcium determination, and histologic (light and electron microscopic) studies showed that completely demineralized allogeneic bone matrix (CDABM) grafts were not rejected and that they stimulated new bone formation at the transplant sites. On the other hand, partially demineralized allogeneic bone matrix (PDABM) grafts were frequently rejected and showed minimal bone induction and gradual demineralization.
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The clinical radiologic, and histopathologic findings of an extremely large traumatic bone cyst have been described. The review of literature, theories of origin, and management of the traumatic cyst have been briefly discussed.
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In rhesus monkeys, data obtained by contrast radiography and hemodynamic and electroencephalographic studies indicate that carotid blood flow is reversible. Results showed that even small amounts of local anesthetic agents when injected inadvertently into a branch of the external carotid artery, may enter the cerebral circulation, most likely through a retrograde flow into the common and then internal carotid arteries. Some toxic neurologic manifestations possibly may be explained by this mechanism.
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Four methyl methacrylate bone substitutes were investigated in bilateral multiple bone defects in the femurs of five rhesus monkeys and five mongrel dogs. The animals were sacrificed at 2, 4, 6, 8, and 10 weeks postoperatively. On the basis of clinical, radiologic, and histologic examination, the Cranioplast evoked the least severe inflammatory response ans was the best biologic bone substitute when compared to Adaptic, Sevitron, and Lucitone.
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One hundred and twenty male albino rats were used to study the regenerative potential of periosteum, and the effects of the size of discontinuity defects on bone repair. The clinical, radiologic, and histological studies disclosed new bone formation and remodeling of fibular fractures and gaps in the presence of periosteum or bone contact, or both. Small and large fibular fracture gaps without periosteum resulted in nonunion, interposition of fibrous tissue, and no new bone formation. It was concluded from the current experimental studies that bone contact is more important than periosteum for normal bone healing. Where contact is not possible, the presence of periosteum assumes a more essential role.