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Biomedical subjects

R Nandwani

Publications and source records attributed to R Nandwani.

31 records · Page 2Linked to original sources
PubMed1994

Hepatitis A seroprevalence in homosexual and heterosexual men.

OBJECTIVE: To determine the seroprevalence of hepatitis A antibodies in homosexual and heterosexual males attending a genitourinary medicine (GUM) clinic. DESIGN: Prospective study of male patients recruited from a GUM clinic during a 10 week period in 1993. SETTING: Central London outpatient GUM department at Chelsea and Westminster Hospital. SUBJECTS: 255 patients were recruited, comprising 185 homosexual and 70 heterosexual males. Ninety two men were known to be HIV-positive, of whom 89 were homosexual. MAIN OUTCOME MEASURES: Serum samples were screened for both IgM and IgG antibodies to hepatitis A by enzyme linked immunoassay. Results were matched to an anonymously completed questionnaire. RESULTS: 81 of the 255 subjects (31.8%) had been exposed to hepatitis A, two of whom were IgM positive. There were similar hepatitis A seroprevalence rates in homosexual (32.4%) and heterosexual men (30.0%). Although 48.1% of the homosexual men were known to be HIV-positive, compared with 4.3% of the heterosexuals. Hepatitis A seroprevalence remained comparable in both groups after patients with known HIV infection were excluded from the analysis. 11.4% of the heterosexual men admitted to oral-anal sexual contact compared with 62.2% of the homosexual men. This sexual practice was not associated with antibodies or a past history of hepatitis A exposure. CONCLUSIONS: There was no detectable difference in hepatitis A seroprevalence between male homosexual and heterosexual GUM clinic attenders, despite a much higher level of oral-anal sexual activity among the homosexual population.

Adult↗
PubMedDate not supplied

Are you sure it's syphilis? A review of false positive serology.

This article on false positive serological reactions for syphilis reviews the rapid developments which have taken place in the serodiagnosis of syphilis in recent years since the advent of the AIDS epidemic. An overview of non-specific and specific treponemal serological tests in relation to acute and chronic biological false positive reactions is followed by closer consideration of syphilis serology in the context of HIV infection, pregnancy and other conditions which may produce false positive reactions.

AIDS-Related Opportunistic Infections↗
PubMedDate not supplied

Human immunodeficiency virus medicine for the MRCP long case and viva.

Doctors should consider human immunodeficiency virus (HIV) disease as a possibility in patients both in the MRCP clinical examination and during daily clinical practice. Aspects relating to the MRCP long case and viva are dealt with in this article.

AIDS-Related Opportunistic Infections↗
PubMedDate not supplied

Human immunodeficiency virus medicine for the MRCP short cases.

Doctors should consider human immunodeficiency virus disease in patients, both in the MRCP clinical examination and during daily clinical practice. This article addresses some aspects of immunodeficiency virus medicine that are not widely discussed in MRCP textbooks.

Clinical Competence↗
PubMedDate not supplied

Modern diagnosis and management of acquired syphilis.

Syphilis presents to clinicians in a wide range of disciplines and requires a high index of suspicion. This article summarizes the interpretation of syphilis serology and provides practical guidelines for the management of acquired syphilis in liaison with local genitourinary medicine physicians.

Antibodies, Bacterial↗