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Biomedical subjects

R Nambiar

Publications and source records attributed to R Nambiar.

51 records · Page 3Linked to original sources

Whole bowel irrigation--an alternative to traditional bowel washout.

The objective of this study was to determine whether or not whole bowel irrigation through oral route was a safe and acceptable alternative to traditional bowel washout per rectum in preparation for large bowel surgery. Out of a total of 114 patients, 32 had whole bowel irrigation, 71 had traditional washout and 11 had no bowel preparation. The irrigation involved approximately 12 litres of normal saline over an average period of 3 1/4 hours. The preparation of the colon by whole bowel irrigation was better as indicated by total absence of faeces and the cleanliness of the colon at operation. However, there was no significant difference in wound infection rate between the two groups although the severity of wound infection was lesser in the first group. There were no major complications like anastomotic breakdown, burst abdomen, abscess or fistula formation and septicaemia in this group. Based on this experience we believe that whole bowel irrigation is a good alternative method of bowel preparation. The advantages of this method are that it is short and rapid, avoiding prolonged pre-operative hospitalisation and is acceptable to most patients.

Aged↗

Cancer of the colon and rectum.

A study was made of 300 surgically treated cases of colorectal cancer during an eight year period. The average age for the disease was 60 years with no sex difference but a low incidence in the younger age group. About 1/3 of the cases presented as emergency and 1/4 with palpable mass. Rectum and sigmoid were the commonest sites, while anal carcinoma was rare. The overall mortality for surgical treatment was 10%. 67.3% were resectable with a mortality of 5%. Although well differentiated adenocarcinoma was the commonest variety, mucinous, colloid and other types were rare. Less than 1/3 of the cases were in favourable Stage A and B, while the majority were advanced. This was the main difference from the reports of western series apart from the rarity of inflammatory and premalignant conditions.

Adult↗

Studies on multiple feeding by Anopheles gambiae s.l. in a Sudan savanna area of north Nigeria.

The detection of haptoglobins in Anopheles gambiae s.l. has been used to obtain an estimate of the incidence of multiple feeding for the village of Barmawa, Garki District, Kano State, Nigeria. The results indicated that the incidence of multiple feeding was approximately 10% but problems were encountered by the high incidence of ahaptoglobinaemia in the population. In four villages in Garki District the incidence of ahaptoglobinaemia varied between 65 and 76% while in young children and personnel under constant malaria chemoprophylaxis it was less than 30%. A strong correlation between ahaptoglobinaemia and malaria infections was seen. The results show evidence of selection of hosts by mosquitoes at Barmawa although this does not necessarily imply a preference per se. The results provide evidence of movement of blood-fed mosquitoes, between houses and from houses to resting sites.

Animals↗

Traumatic closed avulsion of the upper ureter.

Six cases of avulsion injury to the pelvi-ureteric junction due to blunt abdominal trauma are reported. Primary repair was done in three cases and nephrectomy in the rest. The special problems in the diagnosis and treatment are discussed. Pelvi-ureteric junction rupture due to blunt external trauma is a distinct clinical entity. The early diagnosis of the injury is rendered difficult by the paucity of early clinical signs and symptoms. A high index of clinical suspicion and early intravenous pyelography in suspected cases will improve the percentage of cases diagnosed. The treatment of choice is primary repair by ureteropelvic anastomosis. In selected cases where primary anastomosis is not possible procedures such as ureterocalycostomy or the use of an ileal segment may be feasible. As the injury commonly occurs in young children, renal preservation is of paramount importance and nephrectomy should be performed only as a last resort.

Adolescent↗

A case of myasthenia gravis with thyrotoxicosis treated by combined subtotal thyroidectomy and total thymectomy.

Thyrotoxicosis occurring in conjunction with myasthenia gravis is rare. The usual treatment consists of medical control of the thyrotoxicosis, then thymectomy and later subtotal thyroidectomy. The case reported here concerns a 19-year-old girl who had surgical treatment for both lesions on the same occasion. With proper medical preparation, modern anaesthesia and respiratory care, the surgical treatment of both lesions can be accomplished in one stage.

Adult↗