Biomedical subjects
Publications and source records attributed to R N Smith.
Radioimmunoassay, high-performance liquid chromatography and capillary gas chromatography-mass spectrometry were used to detect and measure LSD in the first reported case of fatal poisoning by LSD. The levels found in ante-mortem serum and plasma and in post-mortem blood, liver blood and stomach contents are given.
Eight-eight urine samples were analysed by the EMIT d.a.u. Cannabinoid 20 ng homogeneous enzyme immunoassay, the DPC cannabinoid radioimmunoassay, two in-house cannabinoid radioimmunoassays and a gas chromatography-mass spectrometry method for 11-nor-9-carboxy-delta 9-tetrahydrocannabinol. There was good qualitative agreement between the methods with few discrepancies in the borderline region.
In view of the benefits of hormone replacement therapy (HRT) and the experience that only 10% of women maintain therapy, it is vital that all doctors are familiar with the pros and cons of HRT, so that women may be correctly advised. Here we discuss new issues and developments in HRT and current views on indications, complications and regimens of treatment.