The significance of change in occupational health.
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Biomedical subjects
Publications and source records attributed to R Murray.
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The Division of Biologics Standards of the National Institutes of Health made the Hong Kong variant of influenza virus available to US manufacturers for study in August 1968 and provided them with the Aichi strain for production purposes on 9 September. The first lot of vaccine was released on 15 November; 15 million doses had been released by the peak of the epidemic, which occurred in the first week of January 1969 in the USA, and 20 million doses by the end of that month. Despite the tremendous effort made, however, it is questionable whether the use of the vaccine, necessarily in smaller quantities than the total released, had any detectable effect on the course of the 1968-69 epidemic. The author suggests that it is also doubtful whether the 1957 epidemic of Asian influenza in the USA was significantly affected by the larger amount of vaccine that was then available before the epidemic peak was reached. He stresses that priority must be given to research into the problem of making sufficient vaccine available in good time to counter a threatened influenza epidemic.
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100 consecutive patients with both duodenal ulcer and Campylobacter pylori infection were followed up to see whether eradication of C pylori affected ulcer healing or relapse. Patients were randomly assigned to 8 weeks of treatment with cimetidine or colloidal bismuth subcitrate (CBS), with tinidazole or placebo being given concurrently from days 1 to 10, inclusive. Endoscopy, biopsy, and culture were done at entry, in weeks 10, 22, 34, and 62, and whenever symptoms recurred. There was no maintenance therapy. C pylori persisted in all of the cimetidine-treated patients and in 95% of those treated with cimetidine/tinidazole, but was eradicated in 27% of the CBS/placebo group and 70% of the CBS/tinidazole group. When C pylori persisted, 61% of duodenal ulcers healed and 84% relapsed. When C pylori was cleared 92% of ulcers healed (p less than 0.001) and only 21% relapsed during the 12 month follow-up period (p less than 0.0001).
Programmes were conducted with groups of parents of school-aged, physically handicapped, hearing impaired, and, mildly and moderately mentally handicapped children. In this paper the salient features of the organization of these parent programmes are discussed. Programmes have involved six to eight weekly 2 hour sessions. The format of each session included both lecture presentation and discussion in small groups. Discussions were led by educational psychologists using a combination of reflective and behavioural procedures. Evaluation, by means of post-programme questionnaires and attendance checks, has shown that parents have found programmes to be valuable. An integral part of the parent programmes has been the training of special education teachers in the attitudes and skills necessary for working with parents of handicapped children. The introduction of group programmes is considered to complement the individual training and counselling services already available to such parents in New Zealand.