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Biomedical subjects

R Moscona

Publications and source records attributed to R Moscona.

30 records · Page 2Linked to original sources
PubMed1987

External longitudinal splitting of the tibialis anterior muscle for coverage of compound fractures of the middle third of the tibia.

In this modern era, compound fractures of the middle third of the tibia are relatively common. With the advent of external fixation, these fractures can be more rapidly and effectively dealt with, and attention can be directed to immediate coverage of the exposed bone. External longitudinal splitting of the anterior tibialis muscle offers a convenient and safe method for converting the open fracture to a closed one. The uniqueness of the tibialis anterior muscle is two-fold. It is circumpennate, and it has an internal axial tendon corresponding to almost its total length. Both these features impart to it considerable strength, and the muscle splitting herewith described does not appear to impair its function. Five treated limbs, each with loss of soft tissues overlying compound mid-third tibial fractures, are presented. Rapid healing and virtual absence of bone infection was observed in all cases.

Adult↗
PubMed1986

Early enteral nutrition for mass burn injury: the revised egg-rich diet.

An aggressive enteral nutritional approach has been employed to support our severely burned patients. The diet is based on a daily intake of 5 eggs/10 kg of body weight, incorporated into milkshakes. Twelve patients with severe burns (age, 24 +/- 4 years; burns, 54 +/- 12 per cent of total body surface area (TBSA] were studied. Enteral feeding was initiated on the day of injury and gradually reached the full formula within 3-7 days. Feeding was carried out either orally or through a nasogastric drip or a combination of both, depending on the patient's condition. Each bottle of milkshake contained 2318 kJ, 29 g protein, 51 g carbohydrate and 28.6 g fat in 250 ml. Each millilitre of the diet contained 9.32 kJ. The protein provided 21 per cent of the total calorie intake, while the fat and carbohydrate provided 42 per cent and 37 per cent respectively. The mean daily intake consisted of protein (5 +/- 1.5 g/kg), carbohydrate (8 +/- 0.75 g/kg) and fat (5 +/- 1 g/kg), providing a daily administration of 378-420 kJ/kg. Plasma lipids remained within normal limits during the 40 days of the diet, while serum protein levels rose to normal levels within the first 3 weeks.

Adult↗
PubMed1985

Prevention of gastrointestinal bleeding in burns: the effects of cimetidine or antacids combined with early enteral feeding.

The efficacy of prophylactic therapy with cimetidine or antacids combined with early enteral feeding to prevent gastrointestinal bleeding in patients with severe burns was evaluated. Fifty patients with burns exceeding 30 per cent of the total body surface area (TBSA) were divided into two groups, each of them treated by one of these agents in combination with early feeding. Bleeding was not encountered in either group. It is assumed that the combination of either agent with enteral feeding early in the post-burn course equally protected against gastrointestinal bleeding. Because of the ease and lack of side-effects of cimetidine in this series, its use was preferable.

Adult↗
PubMed1983

Technical variations of the McKissock operation for reduction mammoplasty.

Presented are various modifications of the McKissock vertical bipedicle dermal flap technique for reduction mammoplasty, to enhance the cosmetic and functional results. Virtual elimination of vascular embarrassment of the nipple-areolar complex and largely unimpaired nipple sensation are features of this technique. Suited to this method are a wide variety of enlarged and ptotic breasts.

Breast↗
PubMed1981

The management of laryngotracheal stenosis in burned patients.

Following burns of the upper respiratory tract, laryngotracheal stenosis is associated with considerable morbidity. This paper deals with the cumulative effect of various pathologic processes involved in burn trauma of the upper airway. Emphasis is placed on the extended use of endotracheal intubation and the avoidance of tracheostomy whenever possible. When laryngotracheal stenosis develops, it may be safely and successfully treated by prolonged stenting, as has been borne out by our experience with the T-shaped silicone tubes. Limited reconstructive procedures can be performed to facilitate proper placement of the stent. In our opinion, laryngotracheal resection and reconstruction are not the procedures of choice in burn cases. Our experience in following the preceding guidelines is described. Three illustrative cases serve to exemplify the difficulties and problems involved in the various stages of treatment and the results obtained. The patients are symptom-free 18 to 24 months following stenting, and all enjoy an adequate airway and good voice. There were no complications resulting from this treatment and we suggest that it is worthy of trial.

Adult↗
PubMed1980

Scopolamine and KCl injections into the caudate nucleus. Overtraining-induced protection against deficits of learning.

To test the hypothesis that extended training of an instrumental task prevents the performance impairments seen after cholinergic and generalized blockade of caudate-putamen complex (NC) activity in animals with a relatively low degree of training, groups of rats were trained to press a lever under a continuous reinforcement schedule for 5, 15 or 25 sessions; The effects of microinjections of scopolamine and potassium chloride into the CN were then assessed. In agreement with early studies in cats, a significant deficit in performance was produced in the animals with a low or medium degree of training, while no changes in learned behavior were seen in the overtained rats. These results show that: (a) normal neural activity of the CN is essential for performance of instrumental behavior during acquisition and early maintenance stages but not after overtraining, and (b) that after extended training the encoding necessary for performance may be transferred to another neural system outside the CN.

Animals↗
PubMed1979

A new polymer-iodine combination (iodoplex) for treatment of donor sites: a preliminary controlled study.

A recently introduced polymer preparation (Iodoplex) is described. It is based on a new type of hydrophilic polymeric carrier into which iodine can be incorporated to the extent of 50% or more. Its main feature is that the polymer and the petroleum jelly base are water-insoluble. The iodine is slowly released from the polymer by body fluids, which are rich in protein and dead cells. Iodine has been found to be useful in the treatment of donor sites; no pain or discomfort attends its use, and the dressing peels off easily from the healed epithelium. A controlled study comparing iodoplex-impregnated and scarlet red-impregnated gauze on donor sites was carried out, and the use of Iodoplex was found to have some real advantages over scarlet red.

Adolescent↗