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Biomedical subjects

R Moncada

Publications and source records attributed to R Moncada.

At least 55 records · Page 3Linked to original sources
PubMed1982

Ionic and non-ionic contrast media interaction with anticoagulant drugs.

Normal and pathologic human plasmas were incubated with radiographic contrast media, heparin, Dextran-40 and saline. Renografin-60 produced a strong anticoagulant effect and the clotting times were significantly prolonged; the addition of heparin resulted in greatly elevated thrombin time. No such prolongation was noted with Dextran-40. P-297, ioxaglic and ioxithalamic acids also showed similar anticoagulant properties. When dogs were injected with contrast media and heparin, the overall anticoagulant effect lasted for more than 6 hours, while contrast media or heparin effect remained for a short period of time. Clinical significance of contrast media interactions with anticoagulant drugs is discussed.

Animals↗
PubMed1982

Contrast media induced serotonin release in human blood.

Several contrast media were tested for their ability to release serotonin from whole blood. Renografin-60, Hypaque M-75, Vascoray and Conray were incubated with human blood at 37 degrees C for 60 min. Platelet-poor plasma was analysed for serotonin using a high performance liquid chromatographic technique. Seven non-ionic contrast media were similarly incubated and serotonin levels determined. Ionic contrast media induced a greater release of serotonin compared with non-ionic ones. The amount of serotonin was not proportional to iodine concentration in blood. These results suggest that hypertonic solutions of contrast media produce a physical injury to platelets causing them to release their granular contents.

Adult↗
PubMed1981

Diagnosis of dissecting aortic aneurysm by computed tomography.

Computed tomography (CT) of the torso combined with simultaneous intravenous bolus injection of contrast media was used in sixteen patients suspected of having dissected their aorta. All patients had subsequent correlative percutaneous aortography within 24 h of the CT examination. Four patients proved to be normal, one had an aneurysm of the thoracic aorta, and eleven had aortic dissection (five type I, six type III dissection). All eleven patients with aortic dissections were diagnosed by CT and angiography; nine had spontaneous dissections and two had iatrogenic injuries to the aorta. Limitations of this imaging procedure include; inability to detect aortic valvular dysfunction and failure to provide an adequate perspective of aortic branch involvement. Potential benefits include: avoidance of aortogram in some cases, relative non-invasiveness, rapidity and ease of procedure, and less expense, radiation, contrast media, and discomfort to the patient. Early experience with CT-enhancement technique has reliably demonstrated normal as well as abnormal aortic wall morphology. It may have a place as an alternative to the conventional aortogram.

Adult↗
PubMed1980

Computed tomographic demonstration of anomalous inferior vena cava with azygos continuation.

A case of anomalous inferior vena cava with azygos continuation first diagnosed by computed tomography (CT) and later confirmed by venography is presented. In addition to identifying the dilated azygos vein in the chest, CT can determine the direction of flow in the vein by means of a bolus contrast medium injection. Once this is established, a search for the etiology of the dilated vein can be directed to the appropriate anatomic area.

Adult↗
PubMed1979

Computed tomography staging of renal carcinoma.

The ability of fast thire-and fourth-generation scanning devices to supply images of sufficient quality to delineate the kidney, its vascular supply, and surrounding fascial envelope has provided a modality which permits preoperative staging of tumors of the kidney with an accuracy of about 90% in limited series of 20 specimen cases. The unreliability of bolus injection to evaluate tumor extension to the renal vein accounted for two errors.

Adenocarcinoma↗
PubMed1979

Inflammatory gastrointestinal disease presenting as genitourinary disease.

Chronic inflammatory bowel disease, diverticulitis, and appendicitis may be complicated by genitourinary tract problems. Patients with these diseases occasionally present with a genitourinary problem as an initial complaint prior to diagnosis of the underlying primary bowel disease. The correct diagnosis in these difficult cases will be arrived at sooner if the genitourinary manifestations of inflammatory diseases of the bowel are actively considered.

Adolescent↗
PubMed1978

Detection of hepatic amebic abscesses by infusion tomography.

The liver represents a major challenge for radiologic imaging. A simple method of diagnosing acute inflammatory lesions of the liver by infusion tomography is presented. Results of this technique in 48 consecutive patients with amebic abscesses of the liver are described, and their typical appearance is presented. The test also appears to aid in defining the acuteness of the lesion.

Humans↗
PubMed1978

Migratory traumatic cardiovascular foreign bodies.

Six cases of cardiovascular foreign bodies secondary to trauma are presented. The various modes of entry and travel within the vascular are reviewed. Routine radiographic examination and angiography are shown to be the most useful techniques in defining the location and subsequent course of the foreign body in the vascular system.

Adult↗
PubMed1978

Mediastinitis from odontogenic and deep cervical infection. Anatomic pathways of propagation.

Potentially lethal consequences can quickly occur once the mediastinum is subjected to the ravages of an anaerobic infection. Mediastinitis from odontogenic or deep cervical infections is extremely rare in the era of antibiotic drugs. We have recently encountered five such cases, with a rapid spread of the inflammatory process into the mediastinum resulting in a number of local and systemic complications. All were caused by anaerobic bacteria. Awareness of such complications and early roentgenographic diagnosis lead to prompt surgical drainage, proper antibiotic therapy, and survival after a stormy clinical course. The anatomic pathways between the various fascial planes of the neck and mediastinum will be described.

Adolescent↗