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Biomedical subjects

R Mojtabai

Publications and source records attributed to R Mojtabai.

23 records · Page 2Linked to original sources

Interrater reliability of ratings of delusions and bizarre delusions.

OBJECTIVE: The authors evaluated the interrater reliability of ratings of bizarre delusions, addressing limitations of previous studies. METHOD: Fifty randomly selected psychiatrists rated bizarre delusions in 30 case vignettes adapted from a previous study by Spitzer and associates. Estimates of reliability were obtained for definitions of bizarre delusions in the DSM-III, DSM-III-R, and draft DSM-IV criteria for schizophrenia and for the clinicians grouped according to their current and previous experience with psychotic patients. RESULTS: The kappas for ratings of bizarre delusions according to the different definitions and among clinicians with different levels of experience were in the moderate to fair range. CONCLUSIONS: The reliability of ratings of bizarre delusions appears to be less than satisfactory for clinical practice, and the increased weight given to this symptom in modern diagnostic systems does not seem justifiable.

Delusions↗

Fregoli syndrome.

Fregoli syndrome is the delusional belief that one or more familiar persons, usually persecutors following the patient, repeatedly change their appearance. This syndrome has often been discussed as a variant of the Capgras syndrome in the literature, but these two syndromes have different phenomenological structures and age and sex distributions. The author presents a review of 34 cases of Fregoli syndrome in the English and French language literature, discussing the syndrome's definition, aetiology and course. It is suggested that although an organic substrate may be found in some cases, it is the dominant psychotic theme which determines the content of the syndrome.

Adult↗

Impairment in major depression: implications for diagnosis.

A significant change in the criteria for major depressive disorder in the DSM-IV over the earlier editions was the introduction of a criterion of "clinically significant distress and impairment" (criterion C). However, it is not clear that cases of depression which meet this criterion are distinct from cases that do not meet the criterion on characteristics beyond mere severity of illness. This report used data from the National Comorbidity Survey (NCS) to compare the psychiatric and sociodemographic characteristics of cases of DSM-III-R major depression with varying levels of self-rated impairment. The results of the analyses revealed no difference between respondents with different levels of impairment on gender, age of onset, parental history of depression and suicide, duration of illness, and symptom profiles. With regard to the social and psychiatric indicators of severity of illness, on the other hand, there was a gradient for worse outcome among more severely impaired respondents. It is concluded that the less impaired respondents with DSM-III-R major depression cannot be distinguished from the more impaired on illness characteristics that are not related to the severity of illness. Therefore, cases of DSM-III-R major depression with various levels of impairment most probably represent cases of the same illness that vary only in severity.

Adolescent↗