Myotonia dystrophica (a case report).
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Biomedical subjects
Publications and source records attributed to R Misra.
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Effect of feeding lysine and threonine deficient and supplemented rice diets to rats for fifteen days has been studied on the lipids of hepatic smooth (SER) and rough endoplasmic reticulum. The deficient diet reduced protein and phospholipids of SER where as it increased triglycerides contents of both SER and RER compared to rats fed the supplemented diet.
Prostaglandins-E were demonstrated in the aqueous humour, the anterior uvea, and the choroid of rabbits in which type III allergic reactions were produced by two different methods. In general the levels of prostaglandins were found to be higher in those animals in which the immune complexes were formed from autologous rather than heterologous tissue antigens.
Serum sodium, potassium and chloride values were measured before and after pre-operative starvation and after premedication in healthy subjects under going routine surgery, during both temperate and hot weather. No significant change in serum electrolytes occurred during temperate weather either after starvation or after premedication. In hot weather, when the subjects were sweating, a rise in serum electrolytes occurred, indicating fluid deficit of about 1-8 litres after a mean period of starvation of 11 hours; premedication with atropine and diazepam in these subjects was followed by a significant decrease in the serum electrolytes from the previous raised level after pre-operative starvation.
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Mobile genetic elements have been reported in prokaryotes, plants, yeast and Drosophila. The only transposon-like sequences reported for mammalian organisms are closely related to retroviruses, although undoubtedly other transposon families exist within the mammalian genome. Although mobile genetic elements can only be identified as such if their mobility can be demonstrated in existing populations, transposon and transposon-like elements share several common biochemical and structural features. Here we demonstrate that a repetitive human sequence has many of the diagnostic features of transposable elements. This 2.3-kilobase (kb) transposon-like element contains two flanking long terminal repeat (LTR)-like 350-base pair (bp) repetitive sequences, each of which begins with the sequence 5' TG... and ends with ...CA 3'. The transposon-like element is bounded by 5-bp direct repeats. Discrete-length polyadenylated transcripts from HeLa cells are homologous to the transposon-like element. Members of this transposon-like family are found in extrachromosomal circular DNA molecules.
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The body of a 30-year-old woman was received for autopsy. The available medical case records mentioned that she had been married for the past 3 years and had had primary infertility. She had undergone a diagnostic-cum-operative laparoscopy under general anaesthesia in a private nursing home. On laparoscopy, the internal genital organs were normal except for a fimbrial cyst on each side. Chromopertubation was done using methylene blue dye along with diagnostic dilatation and curettage. The patient was extubated and shifted to the recovery room. About 15 minutes later she developed cyanosis and became unconscious. She died despite sustained efforts at resuscitation.
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