Acupuncture analgesia. A psychophysiological explanation.
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Biomedical subjects
Publications and source records attributed to R Melzack.
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Brief stimulation of the upper lip with the tip of a nylon thread frequently produces an " afterglow" sensation that may persist as long as several minutes after cessation of stimulation. The duration of afterglow is increased by strong suggestion, and decreased by vibration of the skin prior to stimulation. The afterglow may be followed by a period of acute "awareness" of the area, distincty different from the stimulus and afterglow sensations. The afterglows produced by a warm stimulator applied to the back often well up into a painful sting.
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Localized changes in oxygen tension were recorded with platinum cathodes placed in the lateral geniculate nucleus in both anesthetized and awake cats. The amplitude of the responses increased with increasing stimulus intensity, but decreased with increasing flash rate. Both increases and decreases in cathode current were produced by steady illumination. The characteristics of the responses suggest that the responses reflect localized variations in blood flow, produced in turn by changes evoked in the tonic neural activity of the lateral geniculate nucleus.