[Questionnaire for determining the knowledge of diabetics about their disease].
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Biomedical subjects
Publications and source records attributed to R Meissner.
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Tranquilizing-analgesics (diazepam-ketamine combination anaesthesia) and O2-injector respiration has proved during a period of 5 years in 270 laryngo-tracheo-bronchoscopies of newborns and infants to be an outstandingly well-controllable anaesthesia applicable by the intravenous route which could be applied without danger of depression of breathing or circulation and without injury of the laryngeal protection reflex in this early period of life by means of a balanced cooperation between operator and anaesthesiologist. No serious complications have been observed. The authors' own experiences in handling of the method are described.
The introduction of the dialogue programme has the advantage that the data are immediately available at any time. From a yearly admission of 400 patients exact information cn be obtained of the work load and the type of work done at the unit. The value of the system can be summarized as follows: 1) data processing and retrieval are easy and do not require special skills; 2) a multiple of data can be processed; 3) older and more recent data can be compared at any time; i.e. previously obtained information is available for use in the current investigation of a problem; 4) statistical and complicated numerical analyses can be made more quickly and more precisely.
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Basing on the pathophysiologic phenomena in oesophagus wall perforation, the authors examine the question whether contrast radiography, increasingly performed of late, deserves preference over Minnigerode's sign in early diagnosis. Although these diagnostic methods do not compete with each other, since they are equivalents, own experience shows that contrast radiographs should be performed sparingly and, moreover, only if mediastinotomy or intrathoracic oesophagotomy could be practised immediately.
Continuous controls of the nystagmus were carried out from the beginning of Menière's attack. There are four different forms of development. As to the direction of the nystagmus and the directional change of nystagmus during an attack, respectively, a possible neurophysiologic explanation can be offered: due to an increased concentration of potassium in the perilymphatic space during a Menière attack there is a depolarization of the synapse between the vestibular receptive cell and the afferent nerve fiber. The potassium concentration determines the extent of depolarization and thus the direction of the nystagmus.
Information about a sudden bilateral hearing-loss in form of sudden deafness due to bitemporal infarct of brain. The difficulties of diagnosis of cortical and subcortical hearing-disturbances are presented in detail.
A brief description of the operative technique and its indications is given. Advantage and disadvantage of this method are compared with other diagnostic and therapeutic methods of operations. Possibilities of mistakes are explained.
In the period from 1970 to 1978 24 patients after transvesical adenomectomy and 76 patients after TUR of the prostate gland underwent a secondary transurethral surgical intervention. Causes were residual adenomas, stenoses of the vesical neck and recidivations of the adenoma. Explanations are given for the differences in the course of the temporary coordination to the primary intervention. The preoperative situation concerning infections, problems of the operation technique and in the case of the TUR the qualification of the resectionists are mentioned. After the TUR as primary intervention clearly less carcinomas were proved in the electro-resectate in comparison to the transvesical adenomectomy.
Seventy-three of 172 patients with sudden deafness had a vestibular participation. The found forms of spontaneous and provoked nystagmus, their partial combination with thermic under- or non-excitability of the labyrinth as well as vertigo complaints of the patients are described, especially in their temporal course during the illness. The frequent vestibular participation during sudden deafness entitles to introduce the term "range of forms of peripheral-vascular conditioned labyrinthine disturbances", whose cornerstones are the sudden isolated peripheral deafness and the sudden isolated peripheral vestibular loss with a number of intermediate forms. In addition to this, the stronger consideration of the vestibular findings during sudden deafness facilitates the otherwise often difficult differential diagnosis of Menière's syndrome: that one differs by the lacking increase of direction-fixed spontaneous or positional nystagmus to the cochlearly injured ear, incidences of central forms of nystagmus, and the possibility of temporal occurrence of the vestibular findings after the cochlear damage.
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10 patients without concomitant hepatic or renal diseases were given brachial plexus block (Winnie) with etidocaine and the plasma concentrations of the drug were measured. The quantity of local anaesthetic was determined solely by the body weight and amounted to 4 mg/kg body weight. The mean peak concentration was 1.39 microgram/ml, the highest single concentration measured was 1.74 microgram/ml. Peak levels were reached within 40 minutes after administration of the local anaesthetic.
The restoration of peripher labyrinthine excitability after sudden unilateral isolated vestibular loss shows a different behaviour: It can happen with or without recovery nystagmus with a numerical nearly equal frequency. In a follow-up of 44 patients with unilateral vestibular loss of vascular genetics the objective and subjective characteristics of both states are described. In explanation of it a lesion of variable etiology in the region of the vestibular artery and a supposition of a not yet or already occured compensation of the disturbed tonus balance in the nuclear area are not sufficient. Rather the origin of the different clinical states of recovery phenomenon must be presumed in all probability as the result of a primary and secondary retrograde degeneration of the vestibular neurons. Thereby the distance of the lesion from the Scarpa ganglion is presumably of decisive importance.
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