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Biomedical subjects

R Martí

Publications and source records attributed to R Martí.

8 recordsLinked to original sources

[Polymorphous light eruption. Study of the infiltrate with monoclonal antibodies].

The lymphocytic infiltrate in ten cases of papular polymorphous light eruption has been studied with monoclonal antibodies. The results show that the infiltrate is mainly formed by T helper-inducer lymphocytes, but T suppressor-cytotoxic cells are also present. Initial data on appearance of OKT6+ cells in the infiltrate are considered.

Adult

[Multiple clear-cell acanthoma].

Clear cell acanthoma is a benign tumor reported by Degos et al. in 1962. Most commonly the acanthoma presents as a solitary nodule on the lower limb in late middle-aged persons. We've found only 11 papers about multiple clear cell acanthoma. We describe a 73 years old patient who had 21 lesions, the highest number found in the literature.

Aged

[Juvenile Duhring's disease. Apropos of 7 cases].

Chronic non hereditary subepidermal blistering diseases are in childhood and present mainly problems on its clinical and histological diagnosis. Immunopathologic, immunogenetic and ultrastructural studies play a definitive role in the classification of this group of entities. In this paper we report and comment seven children affected of dermatitis herpetiformis. The clinical diagnosis was assessed by direct immunofluorescence studies of the skin, which showed granular Ig A deposits at the MBZ. In five out of our seven patients we were able to demonstrate by clinic and laboratory malabsorption syndrome. A bibliographic review of the subject is carried out, stressing specially the differential aspects with other subepidermal blistering disease of the childhood (i. e. bullous pemphigoid and chronic benign blistering disease of the childhood) as well as some other acute and chronic infantile blistering entities.

Adolescent

Specific cutaneous involvement in Hodgkin's disease.

In Hodgkin's disease (HD) specific cutaneous involvement is rare. When it occurs, retrograde lymphatic spread, direct extension from the underlying lymph nodes, and hematogenous dissemination are the mechanisms usually implicated. Among 349 patients with HD diagnosed and followed-up at our institution from 1969 to 1990, three (0.85 per cent) presented specific cutaneous involvement. In two cases with mixed cellularity subtype, skin lesions displayed histologic features similar to those found in the lymph node. Treatment with combination chemotherapy resulted in rapid disappearance of the lesions in two patients but was ineffective in the third. Previous reports of cutaneous involvement in HD, its differential diagnosis, prognostic significance, and treatment are briefly reviewed.

Adult