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Biomedical subjects

R Marshall

Publications and source records attributed to R Marshall.

At least 181 records · Page 10Linked to original sources
PubMed1976

Observations of the pathology of clubbed fingers with special reference to mast cells.

Mast cell counts were made, in tissue samples of normal and clubbed fingers obtained at autopsy, to investigate the possibility that mast cells act as an intermediary in the development of finger clubbing. Quantitative measurements of the composition of the tissues of the normal and clubbed nail bed were also made. The only significant difference in mast cell numbers in clubbed fingers was a decrease in mast cells in the tissues just superficial to the nail. The appearance of the mast cells was normal. The porportion of blood vessels and other tissues was not significantly different from normal.

Cell Count↗
PubMed1975

Variations in bronchial movement.

Studies of bronchial movement in bronchi and bronchioles following routine bronchography are presented with the aid of a magnification technique. Wide variations of calibre were demonstrated on full inspiration and extreme expiration, most marked in the smaller bronchi. During coughing, maximal differences of width were noted in the larger airways, with little change in the smallest bronchi. In order to assess the changes, reference is made to previous records when, using a three-channel writing oscillograph, bronchial measurements, intra-oesophageal pressures and lung volumes were estimated. Critical examination of the borders of the bronchial walls revealed that they were never straight nor truly parallel. They had smooth, undulating outlines, which were seen to alter on serial films. Irregularities in the airways without disease can be considerable, but when destructive changes are present, gross deformities may become apparent. With a full inspiratory effort, bronchial walls may be completely extended and appear normal, but on radiographs taken on expiration weakness of the bronchial wall may be revealed which otherwise would be missed. The inclusion of routine expiratory films on all bronchographic examinations is recommended.

Adult↗
PubMed1975

Disruption of isolated peritoneal mast cells of the rat by human serum and that by other species.

The effect of human sera on isolated peritoneal mast cells of the rat has been studied in an investigation of non-specific mast cell-disrupting factors. This action of the serum shows some correlation with its haemolytic effect but haemolysis is not increased by phospholipase A whereas the effect on mast cells is usually enhanced. Mast cell disruption produced by the sera of other species has also been studied, and it was found that some sera (e.g. that of pig) considerably reduced the mast cell disruption produced by human serum.

Absorption↗