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Biomedical subjects

R Marra

Publications and source records attributed to R Marra.

92 records · Page 6Linked to original sources

Medical treatment of pulmonary embolism.

Anticoagulant treatment with heparin is definitely the most widely used therapeutic modality in pulmonary embolism. Its efficacy is conditioned by the need for an adequate level of anticoagulation to be rapidly attained. Thrombolytic therapy, as compared to heparin seem to favour a more rapid pertusion of obstructed arteries, a decrease in mean pulmonary pressure, a more rapid improvement in right ventricular function, with however no significant decrease in mortality. It is indicated in case of massive pulmonary embolism with or without shock or in case of perfusion defects in at least one lobe.

Anticoagulants↗

Granulocyte colony-stimulating factor-primed leukocyte transfusions in candida tropicalis fungemia in neutropenic patients.

Optimal management of fungemia in neutropenic patients is still controversial. Several reports have already stressed the poor prognosis in invasive candidiasis (80% mortality in several reports). Therefore granulocyte transfusions would appear to be useful in the management of these infections. We report the use of rhG-CSF-primed granulocyte transfusions plus amphotericin B in two neutropenic patients who developed life-threatening systemic fungal infections. This approach was successful and both patients fully recovered from the infection.

Acute Disease↗