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Biomedical subjects

R Mardrus

Publications and source records attributed to R Mardrus.

6 recordsLinked to original sources
PubMed1989

[Postoperative uveitis following extra-capsular extraction and posterior chamber implantation].

We describe significant non infectious post operative uveitis after extracapsular cataract extraction (ECCE) with insertion of a posterior chamber intra ocular lens. We observe three forms of evolution: the acute and early uveitis, quickly resolving; the late-occuring uveitis; and the chronic, recurring uveitis, which suggests that the inflammatory response may be caused by the hypersensitivity to the lens protein which remained after the ECCE. So a phako-anaphylactic reaction may occur.

Autoimmune Diseases↗
PubMed1988

[Phototoxicity of ultraviolet rays on crystalline lens and retina. Study of the optic transmission of implants with or without anti-UV treatment].

The authors have checked absorbing U.V. IOLs. The use of these IOLs seems to be necessary because of the retinal damage due to direct exposure to near U.V., after lens extraction. Since about ten years a growing body of works has shown phototoxicity on lens and retina by U.V. radiation between 392 and 400 nm. This radiation transmitted by the cornea is not absorbed during the first decade. Progressively, cumulative effects of near U.V. on the lens involve fluorescent chromophore formations, pigmentation, and interferes with synthesis of lens proteins, catalyse insoluble proteins. Finally, cataract are produced as well as experimentally with U.V. lasers. In aphakic eyes the risk of retinal damage increases dramatically. Consequently IOLs absorbing U.V. radiation could protect the retina. A spectrographic check of U.V transmittance by standard IOLs and U.V. absorbing IOLs has shown that the U.V. absorbing IOLs block all radiations below 400 nm.

Animals↗