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Biomedical subjects

R Malik

Publications and source records attributed to R Malik.

257 records · Page 15Linked to original sources

Pathological analysis of intracranial tumors.

An analysis of 145 intracranial tumors observed in the Department of Pathology, Maulana Azad Medical College, and associated Irwin and G.B. Pant Hospitals was carried out. The relative frequency of the different tumors, their site, and the age and sex of the patients is reported, and compared with previous reports in the literature.

Adult↗

Flecainide: its value and danger.

Flecainide is an important addition to the therapeutic armamentarium because it is a potent agent for the treatment of paroxysmal supraventricular tachycardia in patients without structural heart disease. Flecainide also may be useful in patients with debilitating nonsustained ventricular arrhythmias in the absence of structural heart disease. It is rarely useful in the management of life-threatening sustained ventricular arrhythmias.

Arrhythmias, Cardiac↗

Evaluation of factors affecting the accuracy of impressions using quantitative surface analysis.

Impression material goes from a plastic to an elastic state during setting. Movement of the impression and excessive seating pressure during this transition can cause distortion in the impressions. The purpose of this study is to determine if the impression distortion is related to movement during setting or to distortion of the putty phase in the two-step impressioning technique. A master model of a maxillary quadrant of teeth was impressed using four different procedures: 1) one-step technique without movement (1S-NM); 2) one-step technique with movement (1S-M); 3) two-step technique without movement (2S-NM); and 4) two-step technique with movement (2S-M). An artificial oral environment and surface analysis technique of the Minnesota Dental Research Center for Biomaterials and Biomechanics were used to produce the impressions and measure their accuracy. A digitized image of the first premolar of the master model was aligned with a digitized image of the first premolar of each epoxy model using AnSur. The root mean squared difference (RMS) between the aligned images is a measure of the distortion. The corresponding RMS values for the different methods were: 1S-NM = 23.7 +/- 9.21; 1S-M = 20.4 +/- 3.9; 2S-NM = 20.5 +/- 7.7; 2S-M = 21.3 +/- 4.4. Statistical analysis using a two-way analysis of variance showed no difference at the 0.05 level of significance. Pairwise comparison using the Tukey method showed that neither technique (one-step vs two-step) nor movement is a significant factor. These results showed that low seating pressure will not cause any greater distortions in the two-step impression technique than in the one-step technique, and minor movement during the setting of the impression material will no cause distortion.

Analysis of Variance↗

Asymptomatic carriage of Cryptococcus neoformans in the nasal cavity of dogs and cats.

Nasal washings, obtained from a random source of dogs and cats, were concentrated by centrifugation and plated onto bird seed agar containing antibiotics. Cryptococcus neoformans var. neoformans was isolated from eight of 56 dogs (14%) and three of 45 cats (7%). More than 100 colonies of C. neoformans were present on the plates from seven of the 11 positive animals. Absence of cryptococcal antigen in the serum of these animals, and failure to demonstrate yeast-like organisms or significant pathology in nasal biopsies, suggests that the nasal cavity of these animals was not infected by C. neoformans but rather that blastoconidia and/or basidiospores were carried asymptomatically. These findings are discussed in relation to the likelihood of the upper respiratory tract being the primary site for cryptococcal infection in dogs and cats.

Animals↗