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Biomedical subjects

R Mai

Publications and source records attributed to R Mai.

47 records · Page 3Linked to original sources
PubMed1992

Juvenile myoclonic epilepsy of Janz: clinical observations in 60 patients.

We studied 60 patients with juvenile myoclonic epilepsy (JME). There was a high positive family history for epilepsy (33.3%). Age at onset of epilepsy ranged from 4 to 18 years with an average of 13.9 years. 88.3% of patients were seizure-free. The most effective drug was valproate. In eight patients drug withdrawal was attempted but all patients relapsed during a follow-up period of 1 year. Video-EEG studies were performed in eight newly diagnosed patients; myoclonic jerks were recorded in five patients.

Adolescent↗
PubMed1992

Intrauterine growth in the offspring of epileptic mothers.

The present paper concerns the fetal growth of 315 newborns of epileptic mothers prospectively followed from the beginning of pregnancy. In comparison with Italian standards, neonatal weight, length and head circumference at birth were below the 10th percentile in respectively 15.7%, 1.1% and 19.2% of the newborns. Weight at birth was above the 90th percentile in 8 cases. Observed frequencies were significantly higher than expected frequencies for both weight and head circumference. The percentage of newborns with a small head circumference increased significantly according to the number of drugs taken by the mother during the first three months of pregnancy: 7.1% with no drug, 16.8% with one drug, 23.6% with two drugs and 50% with three drugs. A statistically significant correlation was found between gestational age-adjusted head circumference and drug-level scores during the first trimester. Head circumferences below the 10th percentile were fewer among newborns treated with CBZ than among newborns treated with either PB or VPA.

Anticonvulsants↗
PubMed1981

Regional differences in pigeon optic tract, chiasm, and retino-receptive layers of optic tectum.

Electron-microscopic examination of the pigeon optic chiasm, tract, stratum opticum, and retino-receptive layers of the optic tectum revealed regional differences at each level. Axonal size in the fiber pathways paralleled that previously reported for pigeon optic nerve, with mean diameter values of 0.96 micrometer for optic chiasm and 1.06 micrometer for optic tract. The dorsolateral aspects of these pathways contained a heterogeneous population of fibers (mean diameter congruent to 1.44 micrometer) similar to that found in the nasal portion of optic nerve, while the ventromedial regions were occupied by a more homogeneous population of smaller fibers (mean diameter congruent to 0.82 micrometer) resembling those observed in the temporal portion of the nerve. The retino-receptive layers of anteroventral optic tectum (avT) differed ultrastructurally from those of posterodorsal tectum (pdT) with respect to the thickness of horizontal dendrites in layer 2-3, the size of optic terminals in layers 2-7, and the number of synaptic contacts per terminal. These findings point towards a regional variation in the processing of visual information throughout the retino-tectal system and suggest that neurons in avT vs. pdT should show differences in the way they modify the neurophysiological characteristics of their respective optic inputs.

Animals↗
PubMedDate not supplied

[Possible factors affecting dilatation of maternal kidney calices in pregnancy].

In a retrospective analysis we examined several factors in regard to the dilatation of the renal calyces during pregnancy in a normal group of 187 pregnant women between 8 and 42 weeks of pregnancy. The dilatation of the calyceal system was more frequent in case of preceded pyelonephritis, in primipara and bipara, and in younger pregnant patients. We found a significant increase of the dilatation with progress of pregnancy.

Adult↗
PubMedDate not supplied

[Ultrasonography of pregnancy-induced dilatation of maternal kidney calices in a normal patient sample].

To examine the physiological changes of the calyceal system during pregnancy, we selected a normal group of 187 pregnant women by anamnestic, clinical, ultrasonic and laboratory findings. The sonographic investigation of renal pelvis, renal calyces and ureters revealed a more frequent and more pronounced dilatation of the right side. The dilatation was more marked as expected by literature. The complete involution post partum occurred mostly during the first ten days. Even after marked dilatations, a parenchymal reduction could not be found.

Adolescent↗
PubMedDate not supplied

[Normal values of color Doppler ultrasound in pregnancy].

In addition to the flowmetrie of aorta fetalis and a. umbilicalis, color flow mapping enables the examination of the renal and middle cerebral arteries in the assessment of the fetal blood circulation. The resistance and pulsatility-indices of aorta fetalis, umbilical artery, renal artery and middle cerebral artery were calculated in a prospective examination of a normal study group of 123 pregnant women. Moreover, ratios were established from the pulsatility-indices of renal artery and aorta fetalis, renal artery and umbilical artery, middle cerebral artery and aorta fetalis, middle cerebral artery and umbilical artery. By the use of these ratios, we hope to detect more reliably changes in the fetal blood circulation.

Adult↗
PubMedDate not supplied

[Color Doppler sonography of peripheral and cerebral fetal vessels in comparison as prognostic criterion in predicting intrauterine distress].

Doppler sonography of the fetal descending aorta, renal artery, middle cerebral artery and umbilical artery in a population of 74 fetuses with a abdominal circumference below the fifth percentile of the reference limits were done. All fetuses were free from structural and chromosomal abnormalities. The pulsatility- and the resistance indices as well as the ratios between these indices from peripheral and cerebral vessels were calculated and correlated to the fetal distress. The measurement of the pulsatility index of the middle cerebral artery provided the best results in predicting the development of fetal distress. Better results were achieved by the use of ratios of pulsatility-indices of various vessels than by the examination of the vessels alone. Our results suggest the usefulness of the examination of the middle cerebral artery and their ratios compared to the renal artery.

Aorta, Thoracic↗