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Biomedical subjects

R Ma

Publications and source records attributed to R Ma.

At least 127 records · Page 7Linked to original sources

[Relation of T-lymphocyte subsets and symptom complex groups of patients with chronic aplastic anemia].

The T-lymphocyte subsets of 38 patients with chronic aplastic anemia (CAA) were measured by monoclonal antibody (McAb) and ABC method and the relationship of T-lymphocyte subsets and symptom complex groups by traditional Chinese medicine theory were also analysed. It was shown that the T subsets of patients with CAA have remarkable changes: Ts (41.3 +/- 11.2%) increased more than the control (22.9 +/- 4.5%), Th/Ts decreased significantly more than the normal control (0.98 +/- 0.38 to 1.59 +/- 0.38). From the group of deficiency of both vital energy and blood to the group of deficiency of Kidney-yang to the group of deficiency of Kidney-Yin to the group of deficiency of both Kidney-Yang and Kidney-Yin, the Th lymphocyte gradually decreased, Ts lymphocyte successfully increased (from 33.8 +/- 7.9% to 57.7 +/- 7.5%), Th/Ts ratio declined (from 1.29 +/- 0.36 to 0.57 +/- 0.19). The Th/Ts ratio of the latter two groups decreased more than the former two groups (P less than 0.01). These results indicated that the T lymphocyte subsets and symptom complex group of patients with CAA were closely related and when deficient Yang affects Yin the immunologic function of body has a more obvious change. This revealed the connotation of Kidney-Yin and Kidney-Yang on the immuno-regulating cells (T lymphocyte subsets) level.

Adolescent↗

[Effects of stimulation of arcuate nucleus on intragastric pressure and peripheral pathway analysis in rats].

The effect of electrical stimulation of arcuate nucleus (ARC) on intragastric pressure (IGP) was examined on 68 Wistar rats anaesthetized with urethan. The results were as follows: (1) Stimulation of ARC could induce an obvious decrease of IGP. (2) This effect was not blocked by atropine but partially by vagotomy. (3) Extirpation of celiac neural plexus or intramuscular injection of phentolamine could obviously reduce the suppression of IGP induced by ARC stimulation, but intramuscular injection of propranolol had no such effect. (4) After vagotomy plus extirpation of celiac neural plexus, IGP could still be made a decrease by stimulating ARC. In view of the present investigation, it is suggested that (1) Both sympathetic nerve and vagus are involved in the reduction of IGP induced by ARC stimulation, the former and the latter routes being respectively mediated by alpha-adrenoceptor and non-cholinergic, non-adrenergic fibres. (2) Humoral factors may be also involved in this effect of ARC stimulation.

Animals↗

[Involvement of locus coeruleus and dorsal raphe nucleus in the reduction of intragastric pressure induced by ACR stimulation].

The effect of electrical stimulation of hypothalamic arcuate nucleus (ARC) on intragastric pressure (IGP) was observed on 80 Wistar rats anaesthetized with urethan. The main results are as follows: (1) Electrical stimulation of ARC could cause an obvious decrease of IGP. (2) The reduction of IGP induced by electrical stimulation of ARC was not affected by intracerebroventricular injection of naloxone. (3) After lesioning of locus coeruleus or dorsal raphe, the effect of ARC stimulation was depressed. The results suggest that the locus coeruleus and dorsal raphe nucleus may be involved in the reduction of IGP induced by ARC stimulation, but without the involvement of beta-endorphinergic neurons.

Animals↗

[Clinical research on repeated infantile respiratory tract infection treated by fang-gan mixture].

131 cases of repeated infantile respiratory tract infection were selected and divided into 3 groups: fang-gan mixture (FGM) group, levamisole group, and the control group. The results showed that the total effective rate of FGM was 97.7%, which was more effective than the levamisole group. Its effective rate still reached 90.9% after 1 month of stopping treatment, and compared with the treatment period, there were no significant differences (P greater than 0.05). There were three parts of changes on clinical manifestation after patients using FGM: (1) The occurrence times reduced obviously; (2) the course of disease shortened obviously; (3) syndrome of patients relieved obviously. FGM was also more effective than the levamisole group in relieving symptoms and signs (P less than 0.05). Both the FGM and the levamisole groups could increase the body immunity function. After treatment both of salivary sIgA and PHA skin test were higher than before treatment (P less than 0.05).

Adolescent↗