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Biomedical subjects

R M Walls

Publications and source records attributed to R M Walls.

18 recordsLinked to original sources

Airway management in the blunt trauma patient: how important is the cervical spine?

Emergency airway management in the patient with blunt trauma is a clinical dilemma. Many of these patients require immediate airway management, but each method carries its own set of risks and benefits. At the heart of the issue is the long-standing belief that oral intubation is hazardous in the presence of an unstable injury to the cervical spine. In this article, the issues surrounding selection of an appropriate technique for airway management are reviewed critically. Recommendations are made for management of the airway in this high-risk group of patients with injury to the cervical spine.

Airway Obstruction

Evidence of increased class I MHC expression on human peripheral blood lymphocytes during acute ethanol intoxication.

Certain ethanol-related diseases in humans have been linked to disorders of immunity. Although humoral and cellular immunity have been studied, the precise mechanisms whereby ethanol use leads to tissue damage remain unknown. In order to explore the hypothesis that ethanol may lead to alteration in expression of tissue Class I major histocompatibility antigen causing an autoimmune phenomenon, a population of acutely ethanol-intoxicated patients was studied. Measurement of Class I major histocompatibility antigen on peripheral blood lymphocytes in this population showed a highly significant (p less than 0.01) increase over controls. The role that this increased antigenicity may play in the evolution of clinical disease is discussed.

Adult

Cricothyroidotomy.

Cricothyroidotomy is a technique used to gain emergency access to the airway through the cricothyroid membrane. Although its use should be reserved for specific circumstances, the procedure is safe and can be performed rapidly. Knowledge of the anatomy of the anterior neck and a specific sequence for performing the cricothyroidotomy generally will result in a good success rate and acceptable complications.

Airway Obstruction

Case report: Brown-Séquard's syndrome associated with histiocytic lymphoma.

Brown-Séquard's syndrome is a rare spinal cord lesion usually produced by penetrating injuries in which ipsilateral hemiparesis and loss of position sense is associated with loss of pain and temperature sensation on the opposite side of the body. Reported here is an unusual cause of the syndrome, and a review of the pathophysiology of the syndrome is presented.

Adult

Stab wounds to the abdomen: failure of blunt probing to predict peritoneal penetration.

A study was conducted to examine the usefulness of blunt probing for evaluation of penetrating abdominal trauma. Ten anesthetized adult beagles weighing 8 to 17 kg were sacrificed by ventricular fibrillation following a standardized resuscitation protocol. Immediately thereafter, the abdomen was shaved and ten stab wounds were placed in the abdomen of each dog with #11 blade. A separate individual probed the wounds sequentially with a cotton swab and predicted on the basis of this examination whether the wound penetrated the parietal peritoneum (deep) or not (superficial). The abdomen then was opened and reflected, by a midline incision, and peritoneal penetration was verified visually by two observers. Statistical analysis of data was performed using the z test for binomial proportions. Fifty-nine of the 100 wounds were found to penetrate the parietal peritoneum. Examiners predicted 35 correctly, but called 24 of 59 superficial. Thirty-eight of 41 superficial wounds were identified correctly; three were incorrectly called deep. Sensitivity was .59 (z = 1.432, P greater than .5); specificity was .93 (z = 5.466, P less than .001). Blunt probing may be a useful technique if peritoneal penetration is determined, but it is inaccurate in predicting peritoneal nonpenetration. If violation of the peritoneum is not determined with this technique, other methods must be used.

Abdominal Injuries

Hyperkalemia: ECG manifestations and clinical considerations.

Hyperkalemia is a common cause of electrolyte induced cardiac conduction disturbance. A well-defined series of changes at the cellular level leads to characteristic evolutionary changes in the surface electrocardiogram. Initial high T waves and shortened intervals give way to prolongation of conduction and lethal dysrhythmias as the serum potassium level rises. The patterns of electrocardiographic changes associated with hyperkalemia are reviewed and an outline of appropriate therapeutic interventions.

Aged

Acute pericarditis.

There are many causes of acute pericarditis (inflammation of the pericardium) and diagnosis is often difficult owing to the dynamic nature of the disease. History and physical examination, augmented by radiographic and ECG studies, will allow the diagnosis to be made in the majority of cases. The ECG typically undergoes a four-stage evolution, and frequent reassessment of the patient is essential. Outpatient treatment is usually successful, although a subgroup of these patients require hospitalization.

Acute Disease

QT interval prolongation.

The QT interval is a function of ventricular repolarization time and is measured from the onset of the QRS complex to the end of the T wave. The length of this interval is inversely related to heart rate. A prolonged QT interval is most often secondary to the use of Type I antidysrhythmic medications (quinidine, procainamide). It is also associated with phenothiazines, organophosphates, hypocalcemia, liquid protein diets and the congenital long QT syndromes. QT prolongation is associated with a variety of ventricular dysrhythmias, most characteristically Torsades des pointes. Treatment consists of correction of the underlying metabolic disorder or discontinuation of the offending medication.

Adrenergic beta-Antagonists

"Cotton fever": a benign febrile syndrome in intravenous drug abusers.

Cotton fever is a benign, self-limited syndrome that may mimic sepsis in intravenous drug addicts. We present an illustrative case and a review of the literature. Serious illness such as pneumonia and infectious endocarditis must always be considered in febrile addicts. However, trivial illness accounts for 16% to 26% of such fevers. Recent evidence suggests that emergency physicians are able to diagnose trivial illness with 93% specificity in febrile adult drug addicts. Short-term observation units may be an alternative to hospital admission for febrile drug users with a presumptive diagnosis of trivial illness and in those in whom the diagnosis of cotton fever is entertained.

Adult

Blindness following minor head trauma in children: a report of two cases with a review of the literature.

The spectrum of closed head injury ranging from asymptomatic to lethal is well described in the literature. In a small number of cases, dramatic neurologic symptoms normally associated with cerebrovascular accident or vascular headache may arise following apparently insignificant head trauma. We report two cases of young males who developed transient blindness accompanied by significant neurologic abnormality following trivial head injuries. These phenomena are previously well documented, and it is believed that in certain individuals, minor head trauma can induce a type of migraine equivalent known as "footballer's migraine" or "posttraumatic cortical blindness." Current knowledge of these two conditions is reviewed.

Accidental Falls