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Biomedical subjects

R M Vetto

Publications and source records attributed to R M Vetto.

At least 73 records · Page 4Linked to original sources
PubMed1975

Cell-mediated immunity in experimental allergic encephalomyelitis: cross reactivity between myelin basic protein and mycobacteria antigens.

Guinea pigs injected with Freund's incomplete adjuvant emulsified with guinea pig spinal cord, purified guinea pig myelin basic protein, or human myelin basic protein showed dermal reactivity to both of the basic proteins as well as to mycobacteria antigens. Animals receiving only mycobacteria antigens expressed dermal reactivity to the sensitizing antigen in addition to basic protein. This cross reactivity may help explain the role of mycobacteria in inducing and protecting against EAE, and may have important implications concerning human demyelinating diseases.

Animals↗
PubMed1972

Transfer factor from guinea pigs sensitive to dinitrochlorobenzene: absence of superantigen properties.

Transfer factor from guinea pigs sensitive to dinitrochlorobenzene was not bound to an immunoadsorbent column that is specific for the dinitrophenyl determinant. The absence of the dinitrophenyl determinant on transfer factor suggested that the factor does not function as superantigen. The duration of the adoptive sensitivity, the small molecular weight, and the polypeptide or polynucleotide (or a combination) composition of the transfer factor are consistent with a derepressor function of the molecule.

Animals↗
PubMed1971

Delayed Hypersensitivity Induced in Guinea Pigs by 7, 12-Dimethylbenz(a) anthracene.

A delayed hypersensitivity to 7, 12-dimethylbenz(a)anthracene was elicited in guinea pigs after contact sensitization. This sensitivity was characterized by its time of appearance, histology, specificity, and transfer characteristics. The reaction had its maximal dermal reactivity 24 hr after challenge, was characterized by a mononuclear cell infiltration, demonstrated immunological specificity, and could be transferred with leukocytes to normal animals.

Journal Article↗