Search PubMed⌕ Search

Biomedical subjects

R M Tiwari

Publications and source records attributed to R M Tiwari.

47 records · Page 3Linked to original sources
PubMed1981

Electroglottographic studies of Staffieri neoglottis.

Among several methods of surgical restoration of voice which were introduced in the last two decades, the one of Staffieri has so far been most successful, though perfection with this technique still remains to be achieved. Question has always been raised as to the nature of function of the neoglottis in the production of voice in these patients. An attempt has been made to study this function with the aid of electroglottography. Results show that the neoglottis functions in some ways similar to the normal human glottis, and as the source of vibrations in these laryngectomized subjects.

Esophagus↗
PubMedDate not supplied

Experiences with the deltopectoral flap in reconstructive surgery of the head and neck.

Despite the development of many alternative methods of reconstruction in head and neck surgery, the deltopectoral skin flap still remains a useful method in our armamentarium. Its use as a nondelayed procedure in 44 patients with various defects in the head and neck following tumor surgery is discussed. The reliability of the deltopectoral flap is evaluated. Major necrosis of the flap occurred in 6 (13.6%) of our patients. As to the cause of failure, more than one factor could be identified in the individual patient. However, the failure rate was higher when the flap was used in the reconstruction of defects in the anterior part of the oral cavity, particularly the floor of the mouth, than at other sites in the head and neck.

Adult↗
PubMedDate not supplied

Vertical partial laryngectomy for recurrent glottic carcinoma after irradiation.

Vertical partial laryngectomy after a full course of irradiation was performed in 26 patients as salvage surgery for recurrent or residual glottic carcinoma. An excellent cure rate and conservation of function was obtained, while complications were few. A prerequisite for this type of surgery is a limited extent and infiltration of the recurrent local tumor growth. As the great majority of local recurrence appears within the first 2 years after radiotherapy, frequent follow-up during this period is stressed for early detection of a recurrence.

Carcinoma, Squamous Cell↗
PubMedDate not supplied

False-positive and false-negative neck nodes.

We report our experience of the incidence of false-positive (i.e., clinically positive and histologically negative) and false-negative (i.e., clinically negative and histologically positive) neck nodes and define their relationship to the primary site, T-stage, and the histologic grade of the primary lesion. Clinical and pathologic records of 255 patients with squamous cell carcinoma (SCC) of the head and neck who underwent 266 radical neck dissections were reviewed. We did not find any relationship between the T-stage of the primary tumor and the incidence of the false-positive and false-negative neck nodes. Regarding the primary site, the benefit of an elective neck dissection is likely to be maximum in oropharyngeal SCC and minimum in supraglottic SCC. The incidence of false-negative neck nodes was lower in well differentiated primary lesions.

Carcinoma, Squamous Cell↗
PubMedDate not supplied

Long-term results of concurrent polychemotherapy and radiotherapy in patients with stomal recurrence after total laryngectomy.

From 1978 through 1985, eight patients with stomal recurrence after total laryngectomy were treated with a combination of a cytotoxic regimen (vincristin sulfate, bleomycin, and methotrexate [VBM]) and radiotherapy. The essential feature of this combination is the synchronous administration of pulses of VBM and fractionated doses of external radiotherapy in order to achieve potentiation of radiotherapy. On average, four to five pulses of VBM were given. Severe mucositis is the main problem during treatment. Two patients needed nasogastric tube feeding, and treatment was carried out as an inpatient procedure. Five patients are alive with complete local remission at 7 years, 3 years, 2 1/2 years, 14 months, and 8 months after treatment. These results appear to be spectacular, even though the number of patients is small. Of the three patients who died, only one had recurrent disease around the tracheostoma. The two other patients were free of disease in the neck when they died 6 and 16 months after treatment of, respectively, lung metastases and a second primary tumor in the lung. Patients with stomal recurrence after total laryngectomy are now routinely treated with synchronous VBM and radiotherapy.

Aged↗