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Biomedical subjects

R M Sullivan

Publications and source records attributed to R M Sullivan.

79 records · Page 5Linked to original sources
PubMed1986

Early olfactory learning induces an enhanced olfactory bulb response in young rats.

During postnatal days 1-18, pups were simultaneously exposed to an odor and reinforcing tactile stimulation similar to that normally received from the dam. Control pups received only the odor, only the stimulation, or neither of these stimuli. On postnatal day 19, pups that had previously received simultaneous odor and tactile stimulation displayed both a behavioral odor preference and an enhanced 2-deoxyglucose uptake in specific olfactory bulb glomeruli to subsequent presentation of that odor. These results suggest that early olfactory learning enhances the neural response to odors that have acquired attractive value.

Animals↗
PubMed1986

The anterior midline cortex and adaptation to stress ulcers in rats.

Rats with bilateral radio-frequency lesions of the anterior midline cortex were subjected to either single or repeated immobilization stress treatments. As previously demonstrated, the lesions greatly reduced gastric pathology in the acute stress treatment. Conversely, the lesions were found to aggravate gastric pathology in animals stressed repeatedly, thus eliminating the adaptive (i.e., pathology-reducing) effects of repeated stress seen in controls. The role of the anterior midline cortex in stress and stress adaptation is discussed with reference to noradrenergic mechanisms.

Adaptation, Physiological↗
PubMed1986

A prehospital approach to multiple-victim incidents.

Although most prehospital systems have well-developed protocols for single-victim rescues and mass casualties, multiple-victim incidents falling between the two in scope have not been analyzed in detail. Forty-one audio tapes of incidents with four or more victims were evaluated for techniques and decisions that affected the runs' speed and efficiency. Common problems both in the field and at the base hospital were identified. Recommendations for management in the field and for paramedic and base station transmissions are given.

Disaster Planning↗
PubMed1985

Odor familiarity alters mitral cell response in the olfactory bulb of neonatal rats.

Previous studies have shown that rat pups have an enhanced metabolic activity to familiar odors in specific glomeruli of the olfactory bulb. The present study examined extracellularly recorded mitral cell responses to odors in this glomerular region, in odor-familiar and odor-unfamiliar pups. Mitral cells in odor-familiar pups had significantly fewer excitatory and more inhibitory responses to the familiar odor than controls. There were no differences between groups in responses to a novel odor. These results demonstrate that neonatal exposure to odors selectively alters subsequent mitral cell responsiveness to that odor.

Animals↗
PubMed1985

Kindling in the amygdala and susceptibility to stress ulcers.

Kindling in the centromedial amygdala facilitated the subsequent development of restraint-induced stomach ulcers in rats. It was suggested that the neuronal hyperexcitability produced by the kindling procedure led to an increased susceptibility to gastric pathology in response to stress.

Amygdala↗
PubMedDate not supplied

Load factor control for implants in the posterior partially edentulous segment.

There are inherent biomechanical differences in the implant treatment of completely edentulous arches and posterior partially edentulous segments. The partial prosthesis does not benefit from cross-arch stabilization and is, therefore, more susceptible to bending loads. Because of the difference in mobility between teeth and implants, implants may carry a major share of load when mixed with teeth in the same quadrant. However, the frequency of implant overload in posterior partial restorations is low, and, with appropriate treatment planning, overload in these situations is almost always preventable. A checklist procedure is proposed to help the clinician enumerate and evaluate deleterious load factors. By screening patients for such factors in advance, the clinician may identify and avoid potential overload situations when conceiving and fabricating implant-supported posterior partial prostheses. A second checklist, for use at follow-up appointments, lists alarm factors that serve as an early warning of overload once the prosthesis is in place.

Bite Force↗