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Biomedical subjects

R M Rhatigan

Publications and source records attributed to R M Rhatigan.

35 records · Page 2Linked to original sources
PubMed1977

Mucoepidermoid carcinoma of the thyroid gland.

A 20-year-old euthyroid white woman presented with two palpable thyroid nodules. The scintiscan showed an area of increased uptake in the isthmus corresponding with one of the palpable nodules. The uptake in the rest of the gland was diminished including the area of the second palpable nodule which was in the superior portion of the left lobe. Microscopic examination revealed diffuse lymphocytic thyroiditis, follicular adenoma and the isthmus and mucoepidermoid carcinoma of the upper left lobe. No primary site for the muceopidermoid carcinoma outside the thyroid has been identified. Mucoepidermoid carcinoma of the thyroid gland has not previously been reported; the literature is briefly reviewed and etiologic considerations are discussed.

Adenoma↗
PubMed1977

Benign (nonpolypoid) mucosal changes adjacent to carcinomas of the colon. A light microscopic study of 20 cases.

Numerous reports deal with the presence or absence of remnants of benign polyps adjacent to colonic carcinomas. Little attention has been paid to light microscopic mucosal alterations of a nonpolypoid nature found adjacent to these neoplasms. The general assumption has been that this mucosa is normal or not significantly altered. In this presentation we describe nonpolypoid mucosal changes found adjacent to 20 randomly selected carcinomas of the colon. We found these changes to be variably but consistently present. Their possible significance is briefly discussed.

Adenocarcinoma↗
PubMed1977

Unilateral salpingitis due to Enterobius vermicularis.

A case of perforated unilateral salpingitis in which Enterobius vermicularis ova were identified in the inflammatory process is reported. Arguments for considering the parasite to be of etiologic significance in the production of the pathologic changes and clinical symptoms are presented. The infrequent occurrence of symptoms associated with ectopic localization of Enterobius vermicularis is emphasized by a review of the literature.

Adult↗
PubMed1977

Condyloma acuminatum and squamous carcinoma of the vulva.

Reported is the association of condyloma acuminatum and squamous carcinoma of the vulva in three cases and condyloma followed by squamous dysplasia in a fourth case. This association has previously been reported in both male and female genitalia and in the perianal area. In our four cases, cancer or squamous dysplasia followed long-standing or extensive condyloma, but there was no evidence of transformation from condyloma to carcinoma. In one of the cases, areas of squamous dysplasia occurred in multiple foci within a large condyloma. It is not known whether condyloma acuminatum is a precancerous skin lesions, but long-standing or extensive condylomas should alert one to the possibility of carcinoma.

Adult↗
PubMedDate not supplied

Conjunctival melanoma in the black population.

Melanoma of the conjunctiva is a rare, unilateral malignancy primarily affecting middle-aged whites; the annual average age-adjusted incidence rate is 0.012 per 100,000 population. Although conjunctival melanoma in the black population is extremely rare, cases have been reported. Melanoma of skin in blacks has a predilection for nonsun-exposed, nonpigmented sites such as mucous membranes, palms, and soles. Primary acquired melanosis may lead to the development of melanoma even in blacks. Primary acquired melanosis in the black population may be difficult to differentiate from racial melanosis clinically and histopathologically. Early diagnosis through awareness and education can help improve the survival of black patients with conjunctival melanoma.

Antigens, Neoplasm↗