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Biomedical subjects

R M Phillips

Publications and source records attributed to R M Phillips.

At least 91 records · Page 5Linked to original sources

Preneoplastic and neoplastic changes in colonic mucosa in Crohn's disease.

In order to further substantiate the associated risk of colonic adenocarcinoma in cases of Crohn's disease, colonic mucosa from 12 patients with documented Crohn's disease was studied. All of the cases exhibited a wide spectrum of mucosal changes. These changes included the following: dilation and distortion of the crypts, cellular basophilia with decreased mucus, Paneth's cell metaplasia, variable degrees of atypia, and carcinoma in situ. These findings are consistent with the increased incidence of carcinoma of the colon in cases of Crohn's disease.

Cell Transformation, Neoplastic↗

Congenital microhydranencephalus in cattle.

Hydranencephaly with porencephalic cavitation of the cerebellum was diagnosed, over a 2-year period, in five calves from an 80-cow herd. Affected calves were blind and exhibited fine head tremors and limb rigidity. Bovine virus diarrhea-mucosal disease (BVD-MD) antigens, found in the tissues of two calves, were considered to be the likely cause.

Anencephaly↗

The ramus frame implant.

Many procedures for increasing the denture-bearing area of the atrophic mandible have been advocated. This article presents an alternative method of treatment. The ramus frame implant is a metallic tripodal device designed to provide a denture-bearing surface when inserted into the mandible. The procedure for placement of the frame requires minimal time and instrumentation, and it may be performed on an outpatient basis. Fifty-six implants have been placed since 1974, and 51 (91%) are still in place and functional.

Adult↗

Evaluation of a bovine viral diarrhea vaccine produced in a porcine kidney cell line.

An attenuated bovine viral diarrhea (BVD) live-virus vaccine, produced in a continuous porcine cell line, evoked an immune response which produced a protective level of serum antibodies in vaccinated cattle. Post-vaccinal reactions to the vaccinal virus were not observed in cattle vaccinated at 5 feedlots or in cattle vaccinated in experimental tests. The vaccinal virus did not produce demonstrable viremia or detectable excretion of virus from the respiratory or digestive tracts. Leukopenia or abnormality in differential leukocyte values did not occur as with virulent BVD viral infection. Transmission of vaccinal virus from vaccinated cattle to susceptible controls did not occur under conditions in which vaccinated and nonvaccinated cattle were in constant contact for 28 days.

Animals↗